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3D chromatin architecture identification in B cells by MicroC

MicroC libraries were built using B cells from three healthy donors to investigate the 3D chromatin architecture at nucleosome resolution. This approach enables detailed mapping of chromatin interactions, including loops, domains, and higher-order structures. The resulting data can be used to compare the spatial genome organization in B cells with that of other cell types, shedding light on cell-type-specific chromatin regulation.

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Single-nucleus epigenomic profiling of the adult human central nervous system unveils epigenetic memory of developmental programs.
Nat Neurosci 29: 2026 992-1006
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