Integrated drug screening and molecular profiling in pediatric AML

This study aims at identifiying functional-genomic predictors of patient risk in pediatric AML by performing image-based drug response profiling and comprehensive molecular profiling on primary pediatric AML samples

Type: Exome Sequencing
Archiver: European Genome-Phenome Archive (EGA)

1 Dataset 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD50000001572	This dataset contains whole sequencing data from 30 patients with pediatric AML. For each patient, there is one dataset derived from tumor cells and one dataset derived from a matched non-malignant control.	Illumina NovaSeq 6000	60

Publications	Citations
Image-based drug screening combined with molecular profiling identifies signatures and drivers of therapy resistance in pediatric AML. Haladik B, Maurer-Granofszky M, Zoescher P, Jimenez-Heredia R, Frohne A, Segarra-Roca A, Casey C, Kartnig F, Giuliani S, Rashkova C, Repiscak P, Dworzak MN, Superti-Furga G, Boztug K. Cell Rep Med 6: 2025 102304	0