Fluctuating DNA methylation tracks cancer evolution at clinical scale

Long-read Nanopore data of fCpGs from Gabbutt & Duran-Ferrer (2025) for developing the EVOFLUx method to study cancer evolution via DNA methylation fluctuations.

Type: Epigenetics
Archiver: European Genome-Phenome Archive (EGA)

1 Dataset 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD50000001697	Bam files with all reads covering 976 fCpGs identified in Gabbutt and Duran-Ferrer 2025 to develop the EVOFLUx methodology. These include 10 samples, 6 normal B cells, and 2 CLL patients developing RT.	unspecified	10

Publications	Citations
Fluctuating DNA methylation tracks cancer evolution at clinical scale. Gabbutt C, Duran-Ferrer M, Grant HE, Mallo D, Nadeu F, Househam J, Villamor N, Müller M, Heath S, Raineri E, Krali O, Nordlund J, Zenz T, Gut IG, Campo E, Lopez-Guillermo A, Fitzgibbon J, Barnes CP, Shibata D, Martin-Subero JI, Graham TA. Nature 645: 2025 764-773	0