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CLUSTER RNAseq Study of healthy control cohort

CLUSTER aims to discover novel disease mechanisms and biomarkers in children suffering from Juvenile idiopathic arthritis (JIA). Healthy controls were used as the control for baseline expression compared to children with JIA. The samples used in this study comes from blood samples that were collected from healthy volunteers recruited through Centre for Adolescent Rheumatology Versus Arthritis, spanning from children to adult age. These samples were then processed for PBMC isolation followed by sorting cells into 4 different immune cell types. All of these samples were then sequenced by NovaSeq6000,together with the JIA samples.

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