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Large-scale single-cell whole genome and transcriptome sequencing of normal esophagus epithelium

This study utilizes SMART-PTA, a high-throughput workflow for joint single-cell whole-genome and whole-transcriptome sequencing, to map clonal evolution and phenotypic states in the human aging esophagus. By integrating single-cell phylogenies derived from whole-genome somatic variants with matched transcriptomic profiles, we reconstruct clonal dynamics at high resolution.

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Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD50000002573 5