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Data has been deposited at the European Genome-phenome Archive (EGA), which is hosted by the EBI and the CRG, under accession number EGAS50000001793. Further information about EGA can be found at https://ega-archive.org and The European Genome-phenome Archive in 2021: 10.1093/nar/gkab1059

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Large-scale single-cell whole genome and transcriptome sequencing of normal esophagus epithelium

This study utilizes SMART-PTA, a high-throughput workflow for joint single-cell whole-genome and whole-transcriptome sequencing, to map clonal evolution and phenotypic states in the human aging esophagus. By integrating single-cell phylogenies derived from whole-genome somatic variants with matched transcriptomic profiles, we reconstruct clonal dynamics at high resolution.

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Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD50000002573 Illumina NovaSeq 6000 Illumina NovaSeq X Plus 5