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Probiotics and the EARly Life effects on intestinal bacteria and inflammation in children with Cystic Fibrosis (The “PEARL-CF” Study)

The role of probiotics in children with cystic fibrosis (CwCF) remains unclear. The PEARL-CF study was an international, double-blind, randomized, placebo-controlled study involving CwCF (0–6 years), and assessed the effects of a probiotic on intestinal microbiota and clinical outcomes. A multi-strain probiotic (15 Lactobacillus/Bifidobacterium strains; ∼2-3×1010 CFU daily) or placebo was administered for 12-months and participants followed a further 12-months post-intervention.

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Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD50000002694 Illumina NovaSeq X Plus 1030