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Single-cell DNA sequencing reveals a high incidence of chromosomal abnormalities in human blastocysts

Single cell DNA sequencing data from human preimplantation stage embryos from embryonic day 5 to 8, donated for research

1 Dataset 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD50000002781	The dataset contains single-cell whole-genome sequencing data from 55 good-quality surplus human blastocysts, with trophectoderm (TE) and inner cell mass (ICM) separated where possible. We also included multiple control cell lines with known chromosome alterations.The experiment used scKaryo-Seq, a low-pass single-cell DNA sequencing / karyotyping method. Files are raw fastq files.	unspecified	2545

Publications	Citations
Single-cell DNA sequencing reveals a high incidence of chromosomal abnormalities in human blastocysts. Chavli EA, Klaasen SJ, Van Opstal D, Laven JS, Kops GJ, Baart EB. J Clin Invest 134: 2024 e174483	43