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Sex-specific molecular signatures in persistent pain after whiplash injury

We conducted whole-blood RNA-sequencing at 6 months post-injury in individuals with WAD grade II (WADII)—the most common clinical presentation, characterised by neck pain and restricted movement without frank neurological signs—to compare transcriptional profiles between recovery groups (persistent moderate/severe vs minimal symptoms).

Type: Transcriptome Sequencing
Archive: European Genome-phenome Archive (EGA)

1 Dataset 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD50000002844	Molecular signatures associated with recovery after whiplash injury in a deeply phenotyped WADII cohort using bulk RNA-sequencing. 30 participants with RNA-sequencing selected from the primary cohor assessed for recovery 6 months after injury. To assess transcriptional changes associated with persistent whiplash symptoms, we defined recovery groups were defined 6-month post-injury using whiplash symptoms (0-100 visual analogue scale [VAS]): minimal symptoms (VAS<30/100) and moderate/severe symptoms (VAS 30/100)	Illumina NovaSeq 6000	30

Publications	Citations
Sex-specific molecular signatures in persistent pain after whiplash injury: an exploratory analysis. Fundaun J, Ridehalgh C, Dilley A, Schmid AB, Baskozos G. Pain Rep 11: 2026 e1479	0