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IMMUcan CRCCLB CRC1 cohort

The goal of IMMUcan is to understand how the immune system interacts with tumors and how therapeutic interventions influence this interaction. This cohort includes metastatic colorectal Adenocarcinoma from Hopital Centre Leon Berard (Lyon, France). Comprehensive profiling data are integrated with longitudinally collected clinical information. Cellular profiling of the same tumor samples was performed using multiplex immunofluorescence imaging, imaging mass cytometry, and H&E staining.

Type: Cancer Genomics
Archive: European Genome-phenome Archive (EGA)

2 Datasets

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD50000003113	The goal of IMMUcan is to understand how the immune system interacts with tumors and how therapeutic interventions influence these interactions. This cohort comprises patients with metastatic colorectal adenocarcinoma treated at the Centre Léon Bérard Hospital (Lyon, France). The dataset contains whole-exome sequencing (WES) data generated from tumor samples and analyzed against a sex-matched panel of normals consisting of 60 samples processed within the IMMUcan study using the VEGAN pipeline. The dataset includes single nucleotide variant (SNV) and copy number variant (CNV) calling results.	Illumina Genome Analyzer II	210
EGAD50000003114	The goal of IMMUcan is to understand how the immune system interacts with tumors and how therapeutic interventions influence this interaction. This cohort includes metastatic colorectal Adenocarcinoma from Hopital Centre Leon Berard (Lyon, France) . This dataset contains transcriptomics data processed with the STAR pipeline. Two sequencing kits were employed: Roche KAPA for high-quality RNA samples and Takara SMART-Seq Stranded for samples with limited RNA quantities. It contains gene-level counts.	Illumina Genome Analyzer II	171