Transcriptome analysis of iPSC-derived hepatocytes from Wilson's Disease patients and healthy controls

To identify the differences in global gene expression patterns in WD-specific hepatocytes, we performed RNA-seq analysis. Six WD-specific hepatocytes and 6 healthy-donor (HD) hepatocytes were compared in total. The data suggested that our RNA-seq data were partially validated in the context of ATP7B deficiency and that these overlapped genes might be regulated by ATP7B deficiency among mammalian species in common.

• Type: Case-Control
• Archiver: Japanese Genotype-phenotype Archive (JGA)