Multi-modal single-cell analysis of salivary glands from patients with Sjogren's syndrome

Sjogren's syndrome (SS) is an autoimmune disease that causes salivary gland dysfunction due to immune-mediated destruction. In this study, we apply multi-modal single-cell technologies - single-cell RNA sequencing and T-cell receptor sequencing - to salivary gland lesions, aiming to uncover transcriptional signatures and TCR sequence linked to autoantibody profiles.

• Type: Cohort
• Archiver: Japanese Genotype-phenotype Archive (JGA)