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A Prospective Multicenter Study of Exploring Genomic Correlates of Clinical Outcome in Patients with Metastatic Castration-Sensitive Prostate Cancer Receiving Enzalutamide.

This study aims to characterize the somatic mutational landscape of metastatic castration-sensitive prostate cancer (mCSPC) in a Japanese population using whole-exome sequencing of tumor and matched germline DNA. The objective is to provide a comprehensive catalog of somatic mutations and a resource for understanding prostate cancer genomics and supporting future research.