National Cancer Institute (NCI) TARGET: Therapeutically Applicable Research to Generate Effective Treatments
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The Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Initiative seeks to accelerate research in novel marker and drug development, along with understanding the molecular basis of pediatric malignancy, through identification of genomic changes associated with the following childhood cancers:
- Acute Lymphoblastic Leukemia (ALL) - A fast-growing type of blood cancer in which too many immature white blood cells are found in the blood and bone marrow.
- Acute Myeloid Leukemia (AML) - Another type of blood cancer marked by too many myeloblasts, an alternate type of immature white blood cell, are found in the blood and bone marrow.
- Neuroblastoma (NBL) - Cancer of cells of the sympathetic nervous system.
- Osteosarcoma (OS) - A cancer of the bone that primarily affects children and adolescents.
- Wilms' Tumor (WT) - A cancer of cells in the kidney that can spread to the liver, lung and lymph nodes.
Together these cancers account for the majority of the more than 10,000 childhood cancer ... (Show More)