Study

Whole exome sequencing of colorectal cancer patients from the Nurses' Health Study (NHS) and Health Professionals Follow-up Study (HPFS)

Study ID Alternative Stable ID Type
phs000722 Case Set

Study Description

Colorectal cancer is a molecularly heterogeneous disease. Whole Exome Sequencing from patients diagnosed with colorectal cancer in the NHS and HPFS cohorts will extend our understanding of the genetic changes occurring in specific clinical contexts in the disease. This effort has the potential to discover novel recurrently mutated genes and pathways in colorectal cancer that can be functionally validated and give further insights to colorectal cancer pathogenesis. All exome sequencing was performed at the Broad Institute of Harvard and MIT; samples sequence capture was performed using Agilent SureSelect Human All Exon Kit v2 and sequencing was performed on an Illumina HiSeq 2000.

Archive Link Archive Accession
dbGaP phs000722

Who archives the data?

There are no publications available