Identification of Recurrent SMO and BRAF Mutations in Ameloblastomas

Study ID Alternative Stable ID Type
phs000739 Cohort

Study Description

RNA-seq data from two cases of ameloblastoma was analyzed for candidate gene fusions and point mutations. Recurrent point mutations identified in the RNA-seq data, as well as mutations identified with limited panel targeted deep sequencing, were validated as somatic. Expanding to a larger cohort of 28, one of two activating mutations was found in 80% of cases. No recurrent gene fusions events were identified.

Archive Link Archive Accession
dbGaP phs000739

Who archives the data?

There are no publications available