Post-liver transplant recurrent human hepatocellular carcinoma study (RHCCS)

Study ID Alternative Stable ID Type
phs000782 Longitudinal

Study Description

The whole exome sequencing showed that HERC5 deletion and under-expression associates with shorter: time to tumor recurrence, progression-free, and overall survival in hepatocellular carcinoma (HCC) in two independent studies (p1=0.004, HR1=1.80; p2=0.018, HR2=3.31) totaling 286 HCC patients. Matched primary and recurrent tumors indicated a clonal selection advantage in somatic single nucleotide and copy number variants (CNVs) in recurrent compared to primary tumors of Chinese HCC patients with Wnt signaling most activated.

Archive Link Archive Accession
dbGaP phs000782

Who archives the data?

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