NHLBI TOPMed: Study of African Americans, Asthma, Genes and Environment (SAGE) Study
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This is a case-only pharmacogenetic study of bronchodilator drug response among African American children with asthma. Each participant had spirometry measured using the KoKo PFT System. Participant was administered with 4 puffs of HFA Albuterol. The overall goal is to identify genetic factors which are predictive of drug response in children with asthma. The principal tools include a questionnaire and biological specimen collection. Participants are 8-21 years old at time of recruitment. Children with asthma have physician-diagnosed asthma, symptoms and medications.