NHLBI TOPMed: Genetic Epidemiology of COPD (COPDGene) Funded by the National Heart, Lung, and Blood Institute (NHLBI) in the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program

Study ID Alternative Stable ID Type
phs000951 Case-Control

Study Description

This study contains whole genome sequence data and harmonized phenotype variables produced as part of NHLBI's Trans-Omics for Precision Medicine (TOPMed) Whole Genome Sequencing (WGS) project.

The National Heart, Lung and Blood Institute (NHLBI) Trans-Omics for Precision Medicine (TOPMed) program is designed to generate scientific resources to enhance understanding of fundamental biological processes that underlie heart, lung, blood and sleep disorders (HLBS). It is part of a broader Precision Medicine Initiative which aims to provide disease treatments that are tailored to an individual's unique genes and environment. TOPMed will contribute to this initiative through the integration of whole-genome sequencing (WGS) and other -omics (e.g., metabolic profiles, protein and RNA expression patterns) data with molecular, behavioral, imaging, environmental, and clinical data. In doing so this program seeks to uncover factors that increase or decrease the risk of disease, identify subtypes of disease, and develop more targeted and personalized ... (Show More)

Archive Link Archive Accession
dbGaP phs000951

Who archives the data?

There are no publications available