Study

NHLBI TOPMed: Heart and Vascular Health Study (HVH)

Study ID Alternative Stable ID Type
phs000993 Case Set

Study Description

Objectives
The Heart and Vascular Health Study (HVH) is a case-control study of risk factors for the development of myocardial infarction (MI), stroke, venous thrombosis (VT), and atrial fibrillation (AF). The study setting is Group Health, an integrated health care delivery system in Washington State. Only VT cases and early-onset AF cases are included as part of TOPMed.

Background
The HVH study originated in 1988 with the examination of risk factors for MI. Over the ensuing years, the study has been funded by a series of grants which have added case subjects with stroke, VT, and AF. Study aims focused on the associations of medication use with cardiovascular events, and starting in 1997, the study aims expanded to include genetic associations with cardiovascular disease. Participants recruited in 2009 or later who provided blood samples for genetic analysis were asked for consent to deposit genetic and phenotypic data in dbGaP.

Design
As part of the HVH study, case subjects were identified by searching for ICD-9 codes consistent ... (Show More)

Archive Link Archive Accession
dbGaP phs000993

Who archives the data?

There are no publications available