Study

Heart and Vascular Health Study (HVH)

Study ID Alternative Stable ID Type
phs001013 Case-Control

Study Description

Objectives
The Heart and Vascular Health Study (HVH) is a case-control study of risk factors for the development of myocardial infarction (MI), stroke, venous thrombosis (VT), and atrial fibrillation (AF). The study setting is Group Health, an integrated health care delivery system in Washington State.

Background
The study originated in 1988 with the examination of risk factors for MI. Over the ensuing years, the study has been funded by a series of grants, which have added case subjects with stroke, VT, and AF, and used a common control group. Study aims have focused on the associations of medication use with cardiovascular events. Starting in 1997, the study aims expanded to include genetic associations with cardiovascular disease. Participants recruited in 2009 or later and who provided blood samples for genetic analysis were asked for consent to deposit genetic and phenotype data in dbGaP.

Subjects
Case subjects were identified by searching for ICD-9 codes consistent with MI, stroke, VT, or AF. For VT and AF, cases diagnosed ... (Show More)

Archive Link Archive Accession
dbGaP phs001013

Who archives the data?

There are no publications available