High-throughput single-cell DNA sequencing of acute myeloid leukemia tumors with droplet microfluidics

Study ID Alternative Stable ID Type
phs001627 Longitudinal

Study Description

We developed a novel microfluidic platform to automatically barcode genomic DNA from individual cancer cells. Using this approach, we sequenced acute myeloid leukemia (AML) tumors targeting up to 62 loci relevant for the disease from thousands of cells. We predict that our platform will enable analysis of heterogeneity in AML and improve stratification and therapy selection.

Archive Link Archive Accession
dbGaP phs001627

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