Study

Relapsed Acute Lymphoblastic Leukemia (ALL): Mutational Landscape

Study ID Alternative Stable ID Type
phs001951 Longitudinal

Study Description

Multi-agent combination chemotherapy can be curative in acute lymphoblastic leukemia (ALL). Still, patients with primary refractory disease or those with relapsed leukemia have a very poor prognosis. Here we report the mutational landscape of matched diagnostic and relapsed pediatric and adult ALL samples. Our data provides comprehensive annotation of genetic lesions acquired at relapse and reveals diagnostic and relapse-specific mutational mechanisms in ALL.

Archive Link Archive Accession
dbGaP phs001951

Who archives the data?

There are no publications available