Single-cell analysis of upper airway cells reveals host-viral dynamics in influenza infected adults

Study ID Alternative Stable ID Type
phs002039 Cohort

Study Description

This observational study was designed to determine the cellular tropism of Influenza A and B Viruses (IAV, IBV) from samples taken from the upper respiratory tract collected during routine nasal washes during the 2017-2018 season. Using single-cell RNA sequencing (scRNA-seq) we sought to determine which cell types could be infected, what the cellular response was to infection in both infected and bystander cells, and to compare the intra/inter-host variability of IAV and IBV during a single season at a single healthcare provider location.

Archive Link Archive Accession
dbGaP phs002039

Who archives the data?

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