Study

Transcriptomic and Clonal Characterization of T Cells in the Human Central Nervous System

Study ID Alternative Stable ID Type
phs002222 Case-Control

Study Description

The cerebrospinal fluid (CSF) is thought to be a main route for immune surveillance in the central nervous system (CNS). Understanding the composition and state of CSF in healthy individuals may provide insight into perturbations present during neuroinflammation. Here, we have used single-cell RNA and TCR sequencing to profile CSF and peripheral blood mononuclear cells (PBMCs) from healthy individuals and patients with relapsing-remitting multiple sclerosis (MS), a chronic autoimmmune disease.

Archive Link Archive Accession
dbGaP phs002222

Who archives the data?

There are no publications available