Collaborative Cohort of Cohorts for COVID-19 Research (C4R): Coronary Artery Risk Development in Young Adults Study (CARDIA)

Cohort Description

The Coronary Artery Risk Development in Young Adults (CARDIA) study is a study examining the development and determinants of clinical and subclinical cardiovascular disease and their risk factors. It began in 1985-6 with a group of 5115 black and white men and women aged 18-30 years. The participants were selected so that there would be approximately the same number of people in subgroups of race, gender, education (high school or less and more than high school), and age (18-24 and 25-30 years) in each of 4 centers: Birmingham, AL; Chicago, IL; Minneapolis, MN; and Oakland, CA. These same participants were asked to participate in follow-up examinations during 1987-1988 (Year 2), 1990-1991 (Year 5), 1992-1993 (Year 7), 1995-1996 (Year 10), 2000-2001 (Year 15), 2005-2006 (Year 20), 2010-2011 (Year 25), 2015-2016 (Year 30), and 2021-2022 (Year 35).

Data Being Submitted

• Wave 1 questionnaire data includes 397 variables for up to 2434 CARDIA participants in C4R
• Wave 2 questionnaire data includes 448 variables for up to 1901 CARDIA participants in C4R
• Dried Blood Spot/Serosurvey data includes 7 variables for up to 1332 CARDIA participants in C4R
• Derived data includes 43 variables for up to 2723 CARDIA participants in C4R
• Phenotype data includes 113 variables for up to 2723 CARDIA participants in C4R

• Type: Longitudinal
• Archiver: The database of Genotypes and Phenotypes (dbGaP)