Identification of Novel Immunotherapy Targets in Myeloma

RNA sequencing (RNA-Seq) was performed on 94 multiple myeloma (MM) patient samples. We used genomic subgroup and high-risk markers to identify therapeutic targets, including TNFRSF17, GPRC5D, ITGA4, and LAX1, with low predicted toxicity and high specificity to MM and genomic subgroups such as those with TP53 alterations.

• Type: Case Set
• Archiver: The database of Genotypes and Phenotypes (dbGaP)