DAC

DAC for study: Frequent mutation of the FOXA1 untranslated region in prostate cancer

Dac ID Contact Person Email Access Information
EGAC00001000962 Alexander Wyatt awyatt [at] prostatecentre [dot] com No additional information is available

This DAC controls 1 dataset:

Dataset ID Description Technology Samples
EGAD00001004208 Dataset contains targeted sequencing data of 712 plasma cell free DNA samples and 428 white blood cell samples collected from 428 men with metastatic prostate cancer. Target capture was performed using a hydridization-based custom Roche SeqCap EZ Choice kit, designed to capture all exons of 72 prostate cancer driver genes. Cell free DNA was extracted from 10 mL blood samples. Libraries were sequenced using Illumina HiSeq 2500 or Illumina MiSeq instruments to a median coverage of 750x. 62% of samples had ctDNA fraction above 2% of total cfDNA. Note that "Dataset type" is erroneously listed as "Amplicon sequencing", because "Captured-based targeted sequencing" or "Hybridization-based targeted sequencing" were not available options in EGA at the time of submission. Illumina HiSeq 2500 1140