Targeted sequencing of 72 prostate cancer driver in 712 plasma cell free DNA samples

Dataset contains targeted sequencing data of 712 plasma cell free DNA samples and 428 white blood cell samples collected from 428 men with metastatic prostate cancer. Target capture was performed using a hydridization-based custom Roche SeqCap EZ Choice kit, designed to capture all exons of 72 prostate cancer driver genes. Cell free DNA was extracted from 10 mL blood samples. Libraries were sequenced using Illumina HiSeq 2500 or Illumina MiSeq instruments to a median coverage of 750x. 62% of samples had ctDNA fraction above 2% of total cfDNA. Note that "Dataset type" is erroneously listed as "Amplicon sequencing", because "Captured-based targeted sequencing" or "Hybridization-based targeted sequencing" were not available options in EGA at the time of submission.

1140 samples
DAC: EGAC00001000962
Technology: Illumina HiSeq 2500

Access Policy1 Study Files

Metadata

Request Access

Data Access Policy for the DNA sequencing study included in the study "Frequent mutation of the FOXA1 untranslated region in prostate cancer"

A data access agreement (DAA), based on the example DAA provided by EGA, is to be filled out by the requester, and then by the data access committee (DAC) for the study "Frequent mutation of the FOXA1 untranslated region in prostate cancer".

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID	Study Title	Study Type
EGAS00001003113	Frequent mutation of the FOXA1 untranslated region in prostate cancer	Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID	File Type	Size
EGAF00002049557	fq.gz	546.7 MB
EGAF00002049558	fq.gz	662.9 MB
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EGAF00002051309	fq.gz	570.8 MB
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EGAF00002051334	fq.gz	1.0 GB
EGAF00002051335	fq.gz	302.1 MB
EGAF00002051336	fq.gz	338.2 MB
EGAF00002051337	fq.gz	790.1 MB
EGAF00002051338	fq.gz	877.3 MB
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EGAF00002051377	fq.gz	63.1 MB
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EGAF00002051388	fq.gz	282.2 MB
EGAF00002051389	fq.gz	309.3 MB
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EGAF00002051391	fq.gz	239.7 MB
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EGAF00002051393	fq.gz	110.6 MB
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EGAF00002051687	fq.gz	675.2 MB
EGAF00002051688	fq.gz	682.1 MB
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EGAF00002051706	fq.gz	559.3 MB
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EGAF00002051720	fq.gz	239.8 MB
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EGAF00002051740	fq.gz	394.8 MB
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EGAF00002051742	fq.gz	182.2 MB
EGAF00002051743	fq.gz	558.4 MB
EGAF00002051744	fq.gz	565.8 MB
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EGAF00002051746	fq.gz	493.1 MB
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EGAF00002051800	fq.gz	271.6 MB
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EGAF00002051835	fq.gz	251.2 MB
EGAF00002051836	fq.gz	251.9 MB
2280 Files (937.5 GB)