Stanford Data Access Committee for Breast Cancer Tumor Heterogeneity through Treatment

Dac ID Contact Person Email Access Information
EGAC00001000993 Christina Curtis cncurtis [at] stanford [dot] edu No additional information is available

This DAC controls 1 dataset:

Dataset ID Description Technology Samples
EGAD00001004306 We performed whole-exome sequencing on multiple regions (n=2-3) from four primary untreated breast tumors (n=1 HER2+, n=2 ER+/HER2-, n=1 triple-negative), as well as matched normal. We also performed whole-exome sequencing on one region from the pre-treatment diagnostic core biopsy and multiple regions (n=2-6) from the post-treatment surgical specimen for five HER2+ primary breast tumors, as well as matched normal; all were treated with combination chemotherapy and trastuzumab. Analysis of these specimens allows characterization of breast tumor heterogeneity and clonal evolution. Illumina HiSeq 2500 42