EMBL genome biology research group for structural variation (Strand-seq application)

Dac ID Contact Person Email Access Information
EGAC00001001091 Jan Korbel korbel [at] embl [dot] de No additional information is available

This DAC controls 1 dataset:

Dataset ID Description Technology Samples
EGAD00001004499 In this study, we aimed to identify somatic structural variation of T-cell acute lymphoblastic leukemias (T-ALLs_ from patient-derived xenografts (PDX) at the single-cell level. For this purpose, we performed strand-specific single-cell sequencing of PDX-derived T-ALL relapse samples from two juvenile patients (P1, P33). To validate structural variation detected via scTRIP, we profiled whole exome sequencing (WES) data from P33 (samples taken during initial disease, remission, relapse), and mate-pair sequencing data from P1 (relapse). Illumina HiSeq 2000,NextSeq 500 124