DAC Unravelling the contribution of HIF pathway and its therapeutic potential in human AML leukemia-initiating cells

Pablo Menéndez
pmenendez@carrerasresearch.org

Request Access

Dataset ID	Description	Technology	Samples
EGAD00001008514	We performed single cell RNA sequencing (scRNA-seq) from bone marrow on 11 pediatric (0-14 years-old) and adolescent and young adult (AYA) (15-39 years-old) de novo AML samples (Dx) (4 inv(16), 3 t(8;21) and 4 rMLL). In addition, for some patients also relapse sample was sequenced (2 inv(16), 2 t(8;21) and 3 rMLL). Cells were sorted into CD34+/CD38- and CD34-/CD38+ and sequenced separately.	Illumina NovaSeq 6000	18