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DACs
EGAC00001003012
UCLA WGS data access Committee
Contact Information
Roger Lo
rlo@mednet.ucla.edu
Request Access
This DAC controls 2 datasets
Dataset ID
Description
Technology
Samples
EGAD00001009809
WGS of MAPKi acquired resistant samples from patients and PDX models
Illumina NovaSeq 6000
104
EGAD50000001537
The dataset consists of bulk whole exome sequencing (WES) and whole genome sequencing (WGS) data from baseline and disease-progressed tumors after immune checkpoint inhibitor (ICI) treatment, derived from patients, human cell lines, and mouse models. Whole exome sequencing includes 17 clinical cases and one human cell line model with parental and acquired resistant cell lines (n = 5). Whole genome sequencing encompasses the YUMMER mouse model, including vehicle-treated controls (n = 2) and acquired resistant tumors (n = 3). The sequence reads have been aligned to hg19 and mm9 reference genomes, with mapped files (BAM) made available for analysis.
Illumina HiSeq X
Illumina NovaSeq X
NextSeq 2000
unspecified
66