Institute of Pathological Physiology, First Faculty of Medicine, Charles University

Dr Dmitrij Kazancev
dmitry.kazantsev@lf1.cuni.cz

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Dataset ID	Description	Technology	Samples
EGAD50000001213	MCL cells were isolated from different tissues of five patients with MCL at diagnosis, and at the time of the first clinical relapse after failure of standard immunochemotherapy based on alternation of R(ituximab)-CHOP and R-high-dose-araC. All patients signed informed consent according to the Declaration of Helsinki. Four patients were diagnosed with classical nodal aggressive MCL, and all these patients experienced early relapse (i.e., progression of disease POD < 12 months). One patient was diagnosed with indolent non-nodal MCL and relapsed 9 years after initial MCL diagnosis. The dataset presents single cell RNA sequencing data as well as whole exome sequencing data for these five patients.	Illumina NovaSeq 6000 NextSeq 500	28