Five Mantle Cell Lymphoma Patients Before and After Failure of Standard Chemotherapy
MCL cells were isolated from different tissues of five patients with MCL at diagnosis, and at the time of the first clinical relapse after failure of standard immunochemotherapy based on alternation of R(ituximab)-CHOP and R-high-dose-araC. All patients signed informed consent according to the Declaration of Helsinki. Four patients were diagnosed with classical nodal aggressive MCL, and all these patients experienced early relapse (i.e., progression of disease POD < 12 months). One patient was diagnosed with indolent non-nodal MCL and relapsed 9 years after initial MCL diagnosis. The dataset presents single cell RNA sequencing data as well as whole exome sequencing data for these five patients.
- 19/02/2026
- 28 samples
- DAC: EGAC50000000516
- Technologies: Illumina NovaSeq 6000, NextSeq 500
DUO:0000042 version: 2021-02-23
general research use
This data use permission indicates that use is allowed for general research use for any research purpose.
DUO:0000046 version: 2021-02-23
non-commercial use only
This data use modifier indicates that use of the data is limited to not-for-profit use.
Data Access Policy for IPP 1LF UK DAC
This dataset contains genomic and clinical data from lymphoma patients. Access to this dataset is granted for academic and non-commercial research purposes only. To request access, applicants must: - Provide a brief research statement describing the intended use of the data - Sign the Data Access Agreement (DAA) - Have approval from their institution's ethics review board where applicable - Agree not to attempt to re-identify study participants - Agree to cite the original publication in any derived works Access requests will be reviewed by the Data Access Committee (DAC). Approval is typically granted for a period of one year and can be renewed. Users must agree to: - Use the data only for the approved research purpose - Protect data confidentiality and security - Not share access credentials or transfer data to unauthorized parties - Delete or destroy the data after the approved period - Report any breach of data security immediately For technical questions regarding the dataset, contact Dmitry.Kazantsev@lf1.cuni.cz The data providers make no warranties regarding the accuracy of this data and bear no responsibility for any consequences of its use.
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS50000000825 | Transcriptome Sequencing |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
i
|
|---|---|---|---|---|
| EGAF50000309193 | fastq.gz | 1.9 GB |
|
|
| EGAF50000309194 | fastq.gz | 3.5 GB |
|
|
| EGAF50000309195 | fastq.gz | 3.4 GB |
|
|
| EGAF50000309196 | fastq.gz | 2.1 GB |
|
|
| EGAF50000309197 | fastq.gz | 2.2 GB |
|
|
| EGAF50000309198 | fastq.gz | 4.5 GB |
|
|
| EGAF50000309199 | fastq.gz | 1.8 GB |
|
|
| EGAF50000309200 | fastq.gz | 1.8 GB |
|
|
| EGAF50000309201 | fastq.gz | 4.0 GB |
|
|
| EGAF50000309202 | fastq.gz | 2.3 GB |
|
|
| EGAF50000309203 | fastq.gz | 2.4 GB |
|
|
| EGAF50000309204 | fastq.gz | 3.4 GB |
|
|
| EGAF50000309205 | fastq.gz | 3.4 GB |
|
|
| EGAF50000309206 | fastq.gz | 4.1 GB |
|
|
| EGAF50000309207 | fastq.gz | 4.6 GB |
|
|
| EGAF50000309208 | fastq.gz | 2.0 GB |
|
|
| EGAF50000309209 | fastq.gz | 3.5 GB |
|
|
| EGAF50000309210 | fastq.gz | 3.5 GB |
|
|
| EGAF50000309211 | fastq.gz | 3.4 GB |
|
|
| EGAF50000309212 | fastq.gz | 3.3 GB |
|
|
| EGAF50000309213 | fastq.gz | 5.6 GB |
|
|
| EGAF50000309214 | fastq.gz | 2.6 GB |
|
|
| EGAF50000309215 | fastq.gz | 2.6 GB |
|
|
| EGAF50000309216 | fastq.gz | 4.0 GB |
|
|
| EGAF50000309217 | fastq.gz | 2.6 GB |
|
|
| EGAF50000309218 | fastq.gz | 5.5 GB |
|
|
| EGAF50000309219 | fastq.gz | 4.0 GB |
|
|
| EGAF50000309220 | fastq.gz | 4.0 GB |
|
|
| EGAF50000309221 | fastq.gz | 4.0 GB |
|
|
| EGAF50000309222 | fastq.gz | 3.1 GB |
|
|
| EGAF50000309223 | fastq.gz | 3.1 GB |
|
|
| EGAF50000309224 | fastq.gz | 2.6 GB |
|
|
| EGAF50000309225 | fastq.gz | 12.9 GB |
|
|
| EGAF50000309226 | fastq.gz | 11.7 GB |
|
|
| EGAF50000309227 | fastq.gz | 10.9 GB |
|
|
| EGAF50000309228 | fastq.gz | 12.8 GB |
|
|
| EGAF50000309229 | fastq.gz | 13.9 GB |
|
|
| EGAF50000309230 | fastq.gz | 13.6 GB |
|
|
| EGAF50000309231 | fastq.gz | 14.3 GB |
|
|
| EGAF50000309232 | fastq.gz | 7.2 GB |
|
|
| EGAF50000309233 | fastq.gz | 11.6 GB |
|
|
| EGAF50000309234 | fastq.gz | 12.4 GB |
|
|
| EGAF50000309235 | fastq.gz | 17.1 GB |
|
|
| EGAF50000309236 | fastq.gz | 16.4 GB |
|
|
| EGAF50000309237 | fastq.gz | 16.3 GB |
|
|
| EGAF50000309238 | fastq.gz | 13.7 GB |
|
|
| EGAF50000309239 | fastq.gz | 14.5 GB |
|
|
| EGAF50000309240 | fastq.gz | 12.4 GB |
|
|
| EGAF50000309241 | fastq.gz | 12.9 GB |
|
|
| EGAF50000309242 | fastq.gz | 11.7 GB |
|
|
| EGAF50000309243 | fastq.gz | 11.7 GB |
|
|
| EGAF50000309244 | fastq.gz | 8.2 GB |
|
|
| EGAF50000309245 | fastq.gz | 8.7 GB |
|
|
| EGAF50000309246 | fastq.gz | 15.2 GB |
|
|
| EGAF50000309247 | fastq.gz | 15.8 GB |
|
|
| EGAF50000309248 | fastq.gz | 7.6 GB |
|
|
| EGAF50000309249 | fastq.gz | 17.1 GB |
|
|
| EGAF50000309250 | fastq.gz | 12.7 GB |
|
|
| 58 Files (438.3 GB) | ||||
