PASCAL-MID Data Access Committee

Dr Bjarne K Møller
bjmoel@onerm.dk

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Dataset ID	Description	Technology	Samples
EGAD50000001651	High-throughput amplicon sequencing were performed on CD34+ hematopoietic stem and progenitor cells (HSPCs) derived from 4 healthy donors and one unaffected heterozygous carrier of a CYBB c.252G>A variant causing X-linked granulomatous disease. Targeted genome editing were performed in the HSPCs of CYBA and CYBB genes using CRISPR-Cas9 and recombinant AAV6. To assess gene editing outcomes in CD34+ HSPCs, the targeted loci were amplified from genomic DNA and sequenced on an Illumina iSeq100.	Illumina iSeq 100	127
EGAD50000002531	Illumina and Oxford Nanopore sequencing relating to Wolff et al, 2026, Prime editing of human hematopoietic stem cells for correction of GATA2 deficiency	Illumina iSeq 100 PromethION	13