CEITEC - CF Bioinformatics DAC

Dr Nicolas Blavet
nicolas.blavet@ceitec.muni.cz

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Dataset ID	Description	Technology	Samples
EGAD50000002225	This dataset comprises RNA-seq data from 12 high-quality archival FFPE HPV-negative HNSCC tumor samples, selected for downstream differential expression analysis. Data include raw and processed RNA-seq files generated using short-read 3' sequencing optimized for FFPE material. The dataset was used to evaluate Hedgehog pathway activation and related transcriptional signatures. Sequencing was performed on bulk tumor tissue.	NextSeq 2000	12
EGAD50000002226	This dataset includes WES data from 51 HPV-negative HNSCC tumor samples derived from archival FFPE material. Files comprise processed variant call data used for gene- and pathway-level alteration scoring, as well as the resulting CADD-based analysis file. Sequencing was performed using standard exome capture and short-read DNA sequencing technologies.	NextSeq 2000	53