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Validation of a Haloplex platform for targeted re-sequencing of the exons of 25 genes

We recently used the Agilent SureSelect platform to re-sequence a set of genes known to be mutated in human AML. The results from 10 AML DNA samples were very satisfactory, but the effort required was significant. Thus, we decided to re-sequence the same genes using the Haloplax system for target enrichment in 48 AML samples. We planned to do this using MiSeq and have data from a pilot of 3 samples. The data is promising but coverage appears pathcy so far. However, in order to get a better understanding of the data we will need deeper sequencing. We will need two lanes of HiSeq to get the same degree coverage as Sureselect. his data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001000285 Resequencing

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00000222943 bam 316.3 MB
EGAF00000222944 bam 409.1 MB
EGAF00000222945 bam 490.5 MB
EGAF00000222946 bam 418.5 MB
EGAF00000222947 bam 420.3 MB
EGAF00000222948 bam 337.6 MB
EGAF00000222949 bam 353.3 MB
EGAF00000222950 bam 478.3 MB
EGAF00000222951 bam 404.6 MB
EGAF00000222952 bam 467.8 MB
EGAF00000222953 bam 324.9 MB
EGAF00000222954 bam 341.4 MB
EGAF00000222955 bam 360.5 MB
EGAF00000222956 bam 288.7 MB
EGAF00000222957 bam 421.9 MB
EGAF00000222958 bam 412.0 MB
EGAF00000222959 bam 405.6 MB
EGAF00000222960 bam 339.6 MB
EGAF00000222961 bam 314.8 MB
EGAF00000222962 bam 351.4 MB
EGAF00000222963 bam 289.8 MB
EGAF00000222964 bam 332.7 MB
EGAF00000222965 bam 358.7 MB
EGAF00000222966 bam 430.0 MB
EGAF00000222967 bam 310.8 MB
EGAF00000222968 bam 698.5 MB
EGAF00000222969 bam 268.3 MB
EGAF00000222970 bam 174.0 MB
EGAF00000222971 bam 333.2 MB
EGAF00000222972 bam 298.6 MB
EGAF00000222973 bam 315.9 MB
EGAF00000222974 bam 684.3 MB
EGAF00000222975 bam 340.4 MB
EGAF00000222976 bam 325.0 MB
EGAF00000222977 bam 427.3 MB
EGAF00000222978 bam 291.8 MB
EGAF00000222979 bam 462.3 MB
EGAF00000222980 bam 307.0 MB
EGAF00000222981 bam 816.6 MB
EGAF00000222982 bam 1.5 GB
EGAF00000222983 bam 1.1 GB
EGAF00000222984 bam 1.2 GB
EGAF00000222985 bam 1.3 GB
EGAF00000222986 bam 1.2 GB
EGAF00000222987 bam 1.3 GB
EGAF00000222988 bam 962.9 MB
EGAF00000222989 bam 1.2 GB
EGAF00000222990 bam 1.3 GB
EGAF00000222991 bam 1.4 GB
EGAF00000222992 bam 1.1 GB
EGAF00000222993 bam 1.2 GB
EGAF00000222994 bam 1.1 GB
EGAF00000222995 bam 1.8 GB
EGAF00000222996 bam 1.3 GB
EGAF00000690340 cram 14.8 MB
EGAF00000690341 cram 25.8 MB
EGAF00000690342 cram 25.8 MB
EGAF00000690343 cram 26.4 MB
EGAF00000690344 cram 57.2 MB
EGAF00000690345 cram 29.3 MB
EGAF00000690346 cram 32.4 MB
EGAF00000690347 cram 39.3 MB
EGAF00000690348 cram 25.0 MB
EGAF00000690349 cram 40.1 MB
EGAF00000690350 cram 26.4 MB
EGAF00000690351 cram 64.5 MB
EGAF00000691667 cram 25.9 MB
EGAF00000691668 cram 34.2 MB
EGAF00000691669 cram 41.3 MB
EGAF00000691670 cram 33.9 MB
EGAF00000691671 cram 33.4 MB
EGAF00000691672 cram 30.2 MB
EGAF00000691673 cram 30.9 MB
EGAF00000691674 cram 43.7 MB
EGAF00000691675 cram 37.1 MB
EGAF00000691676 cram 44.2 MB
EGAF00000691677 cram 24.2 MB
EGAF00000691678 cram 28.4 MB
EGAF00000691679 cram 33.1 MB
EGAF00000691680 cram 24.7 MB
EGAF00000691681 cram 33.8 MB
EGAF00000691682 cram 34.9 MB
EGAF00000691683 cram 36.6 MB
EGAF00000691684 cram 34.9 MB
EGAF00000691685 cram 31.4 MB
EGAF00000691686 cram 32.5 MB
EGAF00000691687 cram 25.0 MB
EGAF00000691688 cram 26.9 MB
EGAF00000691689 cram 36.3 MB
EGAF00000691690 cram 36.5 MB
EGAF00000691691 cram 27.3 MB
EGAF00000691692 cram 54.3 MB
EGAF00000691693 cram 26.0 MB
93 Files (35.3 GB)