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The Natural History of Human Prostate Cancer

Whole genome DNA sequencing was used to decrypt the phylogeny of multiple samples from distinct areas of cancer and morphologically normal tissue taken from the prostates of 3 men. For each of three different prostates, multiple tumour samples (4, 5, and 3 depending on the case) and one normal tissue sample were whole genome sequenced with a matched blood sample using the Illumiuna HiSeq platform. Tumour samples were sequenced to a target depth of 50X and normals and blood to a target depth of 30X. As of September 2020, some of the studies using these data include: Cooper et al, Nature Genetics 2015 (PMID: 25730763) Wedge et al, Nature Genetics 2018 (PMID: 29662167) Pan-Cancer Analysis of Whole Genomes, Nature 2020 (PMID: 32025007)

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001000262 Other
ID File Type Size Located in
EGAF00000145141 bam 77.8 GB
EGAF00000145142 bam 88.7 GB
EGAF00000145143 bam 159.7 GB
EGAF00000145144 bam 233.3 GB
EGAF00000507637 bam 162.4 GB
EGAF00000507638 bam 82.7 GB
EGAF00000507639 bam 152.3 GB
EGAF00000507640 bam 152.6 GB
EGAF00000507641 bam 134.3 GB
EGAF00000507642 bam 88.1 GB
EGAF00000507643 bam 155.6 GB
EGAF00000507644 bam 132.5 GB
EGAF00000507645 bam 156.8 GB
EGAF00000507646 bam 148.9 GB
EGAF00000507647 bam 79.0 GB
EGAF00000507648 bam 137.8 GB
EGAF00000507649 bam 126.7 GB
EGAF00000507650 bam 92.1 GB
18 Files (2.4 TB)