Dataset

The Natural History of Human Prostate Cancer

Dataset ID Technology Samples
EGAD00001000689 Illumina HiSeq 2000 18

Dataset Description

Whole genome DNA sequencing was used to decrypt the phylogeny of multiple samples from distinct areas of cancer and morphologically normal tissue taken from the prostates of 3 men. For each of three different prostates, multiple tumour samples (4, 5, and 3 depending on the case) and one normal tissue sample were whole genome sequenced with a matched blood sample using the Illumiuna HiSeq platform. Tumour samples were sequenced to a target depth of 50X and normals and blood to a target depth of 30X.

As of September 2020, some of the studies using these data include:
Cooper et al, Nature Genetics 2015 (PMID: 25730763)
Wedge et al, Nature Genetics 2018 (PMID: 29662167)
Pan-Cancer Analysis of Whole Genomes, Nature 2020 (PMID: 32025007)

Who controls access to this dataset

For each dataset that requires controlled access, there is a corresponding Data Access Committee (DAC) who determine access permissions. Access to actual data files is not managed by the EGA. If you need to request access to this data set, please contact:

ICGC Data Access Compliance Office
Contact person: helpdesk
Email: dcc-support [at] icgc [dot] org
Access information: https://docs.icgc.org/download/data-access/
More details: EGAC00001000010

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