Discovery of resistance mechanisms to the BRAF inhibitor vemurafenib in metastatic BRAF mutant melanoma

Discovery of resistance mechanisms to the BRAF inhibitor vemurafenib in metastatic BRAF mutant melanoma by massively-parallel sequencing of tumour samples. Comparison of genomic characteristics of pretreatment 'sensitive' to recurrence 'resistant' tumours to identify the genetics of drug resistance.

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Studies are experimental investigations of a particular phenomenon. e.g. case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients. Click on one of the Study IDs below to find out more.

Study ID Study Title Study Type
EGAS00001000551 Other
ID File Type Size Located in Quality Control
EGAF00000362606 cram 1.5 GB
EGAF00000362607 cram 1.6 GB
EGAF00000362608 cram 1.6 GB
EGAF00000362609 cram 1.6 GB
EGAF00000362610 cram 1.6 GB
EGAF00000362611 cram 1.6 GB
EGAF00000364677 cram 2.2 GB
EGAF00000364678 cram 2.3 GB
EGAF00000364679 cram 2.4 GB
EGAF00000364680 cram 2.4 GB
EGAF00000364681 cram 2.4 GB
EGAF00000364682 cram 2.3 GB
EGAF00000506541 cram 5.7 GB
EGAF00000506542 cram 5.1 GB
EGAF00000506543 cram 4.8 GB
EGAF00000506544 cram 2.9 GB
EGAF00000506545 cram 3.1 GB
EGAF00000506546 cram 3.4 GB
EGAF00000506547 cram 3.1 GB
EGAF00000506548 cram 3.3 GB
EGAF00000508450 cram 3.0 GB
EGAF00000508451 cram 3.2 GB
EGAF00000508452 cram 3.4 GB
EGAF00000508453 cram 3.2 GB
EGAF00000508454 cram 3.4 GB
EGAF00000508455 cram 1.8 GB
EGAF00000508456 cram 1.7 GB
EGAF00000508457 cram 1.6 GB
EGAF00000508458 cram 2.0 GB
EGAF00000508459 cram 1.6 GB
EGAF00000508460 cram 1.9 GB
EGAF00000508461 cram 1.8 GB
EGAF00000508462 cram 2.0 GB
EGAF00000510980 cram 2.1 GB
EGAF00000510981 cram 2.0 GB
EGAF00000510982 cram 1.9 GB
EGAF00000510983 cram 2.4 GB
EGAF00000510984 cram 2.0 GB
EGAF00000510985 cram 2.3 GB
EGAF00000510986 cram 2.1 GB
EGAF00000510987 cram 2.4 GB
EGAF00000525785 cram 107.0 MB
EGAF00000525786 cram 3.3 GB
EGAF00000525787 cram 3.0 GB
EGAF00000525788 cram 2.9 GB
EGAF00000602455 cram 2.1 GB
EGAF00000602456 cram 2.2 GB
EGAF00000602457 cram 2.9 GB
EGAF00000602458 cram 2.2 GB
EGAF00000602459 cram 2.2 GB
EGAF00000602460 cram 2.7 GB
EGAF00000602461 cram 1.8 GB
EGAF00000602716 cram 1.6 GB
EGAF00000602717 cram 1.7 GB
EGAF00000602718 cram 2.2 GB
EGAF00000602719 cram 1.6 GB
EGAF00000602720 cram 1.7 GB
EGAF00000602721 cram 2.0 GB
EGAF00000602722 cram 1.3 GB
EGAF00000614902 cram 1.8 GB
EGAF00000614903 cram 1.8 GB
EGAF00000614904 cram 1.7 GB
EGAF00000626891 cram 1.3 GB
EGAF00000626892 cram 1.3 GB
EGAF00000626893 cram 1.5 GB
EGAF00000626894 cram 1.5 GB
EGAF00000626895 cram 1.7 GB
EGAF00000626896 cram 1.5 GB
EGAF00000626897 cram 1.8 GB
EGAF00000626898 cram 1.6 GB
EGAF00000642325 cram 2.1 GB
EGAF00000642326 cram 2.4 GB
EGAF00000642327 cram 2.1 GB
EGAF00000642328 cram 1.7 GB
EGAF00000642329 cram 1.6 GB
EGAF00000642330 cram 2.0 GB
EGAF00000642331 cram 1.9 GB
EGAF00000642332 cram 2.2 GB
EGAF00000642333 cram 1.9 GB
EGAF00000642334 cram 2.3 GB
EGAF00000642335 cram 2.1 GB
EGAF00000835908 cram 1.6 GB
EGAF00000835909 cram 1.7 GB
EGAF00000835910 cram 2.3 GB
EGAF00000835911 cram 1.3 GB
EGAF00000835912 cram 1.6 GB
EGAF00000835913 cram 1.5 GB
EGAF00000835914 cram 1.5 GB
EGAF00000859634 cram 1.7 GB
EGAF00000859635 cram 1.8 GB
EGAF00000859636 cram 2.4 GB
EGAF00000859637 cram 1.4 GB
EGAF00000859638 cram 1.7 GB
EGAF00000859639 cram 1.6 GB
EGAF00000859640 cram 1.6 GB
EGAF00000961802 cram 3.8 GB
EGAF00000961803 cram 2.9 GB
EGAF00000961804 cram 3.3 GB
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