Pilot experiment on functional genomics in osteoarthritis_RNA
The aim of this work is to apply an integrated systems approach to understand the biological underpinnings of large joint (hip and knee) osteoarthritis which culminates in the need for total joint replacement (TJR). In this pilot we will assess the feasibility of the approach in the relevant tissue. We will obtain diseased and non-diseased tissue (cartilage and endochondral bone) following TJR, coupled with a blood sample, from 12 patients. We will characterise the 12 pairs of diseased and non-diseased tissue samples in terms of transcription (RNASeq) The pilot will help assess the feasibility of isolating sufficient levels of starting material for the different approaches, and will instigate the development of analytical approaches to synthesising the resulting data.
- 26/05/2015
- 24 samples
- DAC: EGAC00001000205
- Technology: Illumina HiSeq 2000
Wellcome Trust Sanger Institute Data Sharing Policy
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001001203 | Transcriptome Analysis |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
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|---|---|---|---|---|
| EGAF00000792120 | cram | 729.1 MB | Report |
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| EGAF00000792121 | cram | 674.0 MB | Report |
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| EGAF00000792122 | cram | 688.6 MB | Report |
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| EGAF00000792123 | cram | 689.0 MB | Report |
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| EGAF00000792124 | cram | 685.2 MB | Report |
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| EGAF00000792125 | cram | 736.5 MB | Report |
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| EGAF00000792126 | cram | 755.4 MB | Report |
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| EGAF00000792127 | cram | 819.7 MB | Report |
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| EGAF00000792128 | cram | 666.7 MB | Report |
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| EGAF00000792129 | cram | 720.6 MB | Report |
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| EGAF00000792130 | cram | 646.0 MB | Report |
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| EGAF00000792131 | cram | 629.2 MB | Report |
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| EGAF00000792132 | cram | 748.5 MB | Report |
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| EGAF00000792133 | cram | 707.0 MB | Report |
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| EGAF00000792134 | cram | 693.7 MB | Report |
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| EGAF00000792135 | cram | 736.4 MB | Report |
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| EGAF00000792136 | cram | 1.1 GB | Report |
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| EGAF00000792137 | cram | 711.1 MB | Report |
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| EGAF00000792138 | cram | 676.4 MB | Report |
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| EGAF00000792139 | cram | 630.8 MB | Report |
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| EGAF00000792140 | cram | 682.7 MB | Report |
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| EGAF00000792141 | cram | 733.0 MB | Report |
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| EGAF00000792142 | cram | 594.2 MB | Report |
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| EGAF00000792143 | cram | 703.6 MB | Report |
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| EGAF00000792144 | cram | 731.2 MB | Report |
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| EGAF00000792145 | cram | 669.4 MB | Report |
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| EGAF00000792146 | cram | 683.8 MB | Report |
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| EGAF00000792177 | cram | 684.3 MB | Report |
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| EGAF00000792178 | cram | 680.8 MB | Report |
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| EGAF00000792179 | cram | 730.8 MB | Report |
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| EGAF00000792180 | cram | 749.0 MB | Report |
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| EGAF00000792181 | cram | 814.0 MB | Report |
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| EGAF00000792182 | cram | 660.5 MB | Report |
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| EGAF00000792183 | cram | 714.0 MB | Report |
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| EGAF00000792184 | cram | 641.1 MB | Report |
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| EGAF00000792185 | cram | 624.6 MB | Report |
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| EGAF00000792186 | cram | 743.2 MB | Report |
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| EGAF00000792187 | cram | 701.6 MB | Report |
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| EGAF00000792188 | cram | 689.6 MB | Report |
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| EGAF00000792189 | cram | 730.5 MB | Report |
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| EGAF00000792190 | cram | 1.1 GB | Report |
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| EGAF00000792191 | cram | 705.9 MB | Report |
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| EGAF00000792192 | cram | 671.0 MB | Report |
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| EGAF00000792193 | cram | 626.5 MB | Report |
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| EGAF00000792194 | cram | 676.6 MB | Report |
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| EGAF00000792195 | cram | 728.3 MB | Report |
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| EGAF00000792196 | cram | 590.6 MB | Report |
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| EGAF00000792197 | cram | 699.7 MB | Report |
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| EGAF00000792198 | cram | 725.2 MB | Report |
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| EGAF00000792286 | cram | 544.9 MB | Report |
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| EGAF00000792287 | cram | 560.1 MB | Report |
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| EGAF00000792288 | cram | 561.3 MB | Report |
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| EGAF00000792289 | cram | 556.4 MB | Report |
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| EGAF00000792290 | cram | 597.8 MB | Report |
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| EGAF00000792291 | cram | 613.8 MB | Report |
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| EGAF00000792292 | cram | 666.6 MB | Report |
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| EGAF00000792293 | cram | 543.8 MB | Report |
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| EGAF00000792294 | cram | 583.6 MB | Report |
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| EGAF00000792295 | cram | 524.3 MB | Report |
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| EGAF00000792296 | cram | 512.7 MB | Report |
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| EGAF00000792297 | cram | 607.9 MB | Report |
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| EGAF00000792298 | cram | 574.6 MB | Report |
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| EGAF00000792299 | cram | 566.8 MB | Report |
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| EGAF00000792300 | cram | 600.4 MB | Report |
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| EGAF00000792301 | cram | 865.1 MB | Report |
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| EGAF00000792302 | cram | 580.9 MB | Report |
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| EGAF00000792303 | cram | 549.1 MB | Report |
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| EGAF00000792304 | cram | 512.0 MB | Report |
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| EGAF00000792305 | cram | 552.9 MB | Report |
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| EGAF00000792306 | cram | 596.0 MB | Report |
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| EGAF00000792334 | cram | 485.8 MB | Report |
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| EGAF00000792335 | cram | 572.8 MB | Report |
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| EGAF00000792336 | cram | 597.5 MB | Report |
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| EGAF00000792337 | cram | 673.0 MB | Report |
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| EGAF00000792338 | cram | 687.5 MB | Report |
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| EGAF00000792339 | cram | 687.2 MB | Report |
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| EGAF00000792340 | cram | 684.0 MB | Report |
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| EGAF00000792341 | cram | 731.6 MB | Report |
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| EGAF00000792342 | cram | 751.8 MB | Report |
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| EGAF00000792343 | cram | 817.7 MB | Report |
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| EGAF00000792344 | cram | 660.9 MB | Report |
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| EGAF00000792345 | cram | 714.9 MB | Report |
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| EGAF00000792346 | cram | 642.7 MB | Report |
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| EGAF00000792347 | cram | 627.0 MB | Report |
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| EGAF00000792348 | cram | 744.5 MB | Report |
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| EGAF00000792349 | cram | 703.1 MB | Report |
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| EGAF00000792350 | cram | 693.0 MB | Report |
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| EGAF00000792351 | cram | 731.2 MB | Report |
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| EGAF00000792352 | cram | 1.1 GB | Report |
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| EGAF00000792353 | cram | 708.9 MB | Report |
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| EGAF00000792354 | cram | 672.0 MB | Report |
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| EGAF00000792355 | cram | 628.5 MB | Report |
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| EGAF00000792356 | cram | 678.5 MB | Report |
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| EGAF00000792357 | cram | 731.5 MB | Report |
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| EGAF00000792358 | cram | 591.1 MB | Report |
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| EGAF00000792359 | cram | 701.1 MB | Report |
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| EGAF00000792360 | cram | 726.1 MB | Report |
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| EGAF00000792395 | cram | 673.7 MB | Report |
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| EGAF00000792396 | cram | 688.2 MB | Report |
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| EGAF00000792397 | cram | 688.6 MB | Report |
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| EGAF00000792398 | cram | 684.6 MB | Report |
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| EGAF00000792399 | cram | 735.4 MB | Report |
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| EGAF00000792400 | cram | 754.6 MB | Report |
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| EGAF00000792401 | cram | 819.3 MB | Report |
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| EGAF00000792402 | cram | 665.7 MB | Report |
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| EGAF00000792403 | cram | 719.7 MB | Report |
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| EGAF00000792404 | cram | 644.9 MB | Report |
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| EGAF00000792405 | cram | 628.7 MB | Report |
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| EGAF00000792406 | cram | 747.4 MB | Report |
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| EGAF00000792407 | cram | 706.6 MB | Report |
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| EGAF00000792408 | cram | 694.2 MB | Report |
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| EGAF00000792409 | cram | 735.8 MB | Report |
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| EGAF00000792410 | cram | 1.1 GB | Report |
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| EGAF00000792411 | cram | 710.3 MB | Report |
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| EGAF00000792412 | cram | 675.4 MB | Report |
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| EGAF00000792413 | cram | 629.8 MB | Report |
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| EGAF00000792414 | cram | 681.7 MB | Report |
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| EGAF00000792415 | cram | 732.8 MB | Report |
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| EGAF00000792416 | cram | 594.6 MB | Report |
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| EGAF00000792417 | cram | 703.8 MB | Report |
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| EGAF00000792418 | cram | 730.2 MB | Report |
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| EGAF00000792419 | cram | 672.6 MB | Report |
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| EGAF00000792420 | cram | 686.8 MB | Report |
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| EGAF00000792421 | cram | 687.3 MB | Report |
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| EGAF00000792422 | cram | 683.8 MB | Report |
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| EGAF00000792423 | cram | 734.0 MB | Report |
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| EGAF00000792424 | cram | 752.7 MB | Report |
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| EGAF00000792425 | cram | 817.7 MB | Report |
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| EGAF00000792426 | cram | 664.4 MB | Report |
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| EGAF00000792427 | cram | 717.8 MB | Report |
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| EGAF00000792428 | cram | 643.9 MB | Report |
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| EGAF00000792429 | cram | 628.0 MB | Report |
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| EGAF00000792430 | cram | 746.6 MB | Report |
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| EGAF00000792431 | cram | 704.8 MB | Report |
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| EGAF00000792432 | cram | 692.8 MB | Report |
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| EGAF00000792433 | cram | 733.7 MB | Report |
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| EGAF00000792434 | cram | 1.1 GB | Report |
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| EGAF00000792435 | cram | 709.4 MB | Report |
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| EGAF00000792436 | cram | 673.9 MB | Report |
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| EGAF00000792437 | cram | 629.0 MB | Report |
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| EGAF00000792438 | cram | 680.4 MB | Report |
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| EGAF00000792439 | cram | 731.3 MB | Report |
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| EGAF00000792440 | cram | 593.5 MB | Report |
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| EGAF00000792441 | cram | 702.2 MB | Report |
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| 144 Files (99.3 GB) | ||||