Dataset

Whole-genome sequencing in 14 cases and whole-exome sequencing in 90 cases of Chinese ESCC

Dataset ID Technology Samples
EGAD00001001691 Illumina HiSeq 2000 208

Dataset Description

Esophageal cancer is one of the most aggressive cancers and the sixth leading cause of cancer death worldwide1. Approximately 70% of the global esophageal cancers occur in China and over 90% histopathological forms of this disease are esophageal squamous cell carcinoma (ESCC)2-3. Currently, there are limited clinical approaches for early diagnosis and treatment for ESCC, resulting in a 10% 5-year survival rate for the patients. Meanwhile, the full repertoire of genomic events leading to the pathogenesis of ESCC remains unclear. Here we show a comprehensive genomic analysis in 158 ESCC cases, as part of the International Cancer Genome Consortium (ICGC) Research Projects (http://icgc.org/icgc/cgp/72/371/1001734). We conducted whole-genome sequencing in 14 ESCC cases and whole-exome sequencing in 90 cases.

Who controls access to this dataset

For each dataset that requires controlled access, there is a corresponding Data Access Committee (DAC) who determine access permissions. Access to actual data files is not managed by the EGA. If you need to request access to this data set, please contact:

ICGC Data Access Compliance Office
Contact person: helpdesk
Email: dcc-support [at] icgc [dot] org
Access information: https://docs.icgc.org/download/data-access/
More details: EGAC00001000010

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