Resistance to MAPK-inhibitor induces internal duplication in BRAF_Oscar Krijsman
2 BRAFV600E cell lines that have been made resistance to 1. the BRAF inhibitor PLX4720 and 2. the combination therapy of dabrafenib and trametinib seem to have a internal duplication in the kinase domain. We would like to know if this is caused by a translocation.
- 13/08/2016
- 4 samples
- DAC: EGAC00001000000
- Technology: HiSeq X Ten
DUO:0000019 version: 2021-02-23
publication required
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DUO:0000028 version: 2021-02-23
institution specific restriction
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DUO:0000042 version: 2021-02-23
general research use
This data use permission indicates that use is allowed for general research use for any research purpose.
Wellcome Trust Sanger Institute Cancer Genome Group Data Sharing Policy
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001001304 | Other |
