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Cetuximab is a targeted monoclonal antibody against the epidermal growth factor receptor (EGFR) which is used therapeutically for the treatment of KRAS wild-type colorectal cancer (CRC). The Cetuximab sensitive KRAS wild-type CRC cell line NCI-H508 has been treated with a fixed concentration of ENU for 24 hours and then selected with Cetuximab until drug resistant clones were ready to be picked and grown up as sub-clones of the parental cell line. These will have genes causally implicated in cancer sequenced to identify common point mutations in multiple independently derived drug resistant clones as a forward genetic screen for mechanisms of resistance to Cetuximab in CRC

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Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001001745 Cancer Genomics

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00001168364 cram 1.3 GB
EGAF00001168365 cram 971.4 MB
EGAF00001168366 cram 952.6 MB
EGAF00001168367 cram 1.5 GB
EGAF00001168368 cram 1.2 GB
EGAF00001168369 cram 1.3 GB
EGAF00001168370 cram 1.4 GB
EGAF00001168371 cram 1.3 GB
EGAF00001168372 cram 1.2 GB
EGAF00001168373 cram 958.7 MB
EGAF00001168374 cram 940.0 MB
EGAF00001168375 cram 1.4 GB
EGAF00001168376 cram 1.2 GB
EGAF00001168377 cram 1.2 GB
EGAF00001168378 cram 1.4 GB
EGAF00001168379 cram 1.2 GB
EGAF00001168380 cram 779.0 MB
EGAF00001168381 cram 836.8 MB
EGAF00001168382 cram 903.8 MB
EGAF00001168383 cram 780.5 MB
EGAF00001168384 cram 864.7 MB
EGAF00001168385 cram 816.3 MB
EGAF00001168386 cram 714.4 MB
EGAF00001168387 cram 921.2 MB
EGAF00001168388 cram 738.4 MB
EGAF00001168389 cram 892.5 MB
EGAF00001168390 cram 660.8 MB
EGAF00001168391 cram 709.6 MB
EGAF00001168392 cram 960.3 MB
EGAF00001168393 cram 704.2 MB
EGAF00001168394 cram 773.6 MB
EGAF00001168395 cram 831.0 MB
EGAF00001168396 cram 897.3 MB
EGAF00001168397 cram 775.2 MB
EGAF00001168398 cram 858.9 MB
EGAF00001168399 cram 810.4 MB
EGAF00001168400 cram 708.5 MB
EGAF00001168401 cram 914.9 MB
EGAF00001168402 cram 733.2 MB
EGAF00001168403 cram 886.0 MB
EGAF00001168404 cram 655.9 MB
EGAF00001168405 cram 703.9 MB
EGAF00001168406 cram 953.9 MB
EGAF00001168407 cram 699.0 MB
EGAF00001168408 cram 940.1 MB
EGAF00001168409 cram 871.1 MB
EGAF00001168410 cram 752.4 MB
EGAF00001168411 cram 779.8 MB
EGAF00001168412 cram 904.0 MB
EGAF00001168413 cram 606.0 MB
EGAF00001168414 cram 908.3 MB
EGAF00001168415 cram 734.8 MB
EGAF00001168416 cram 743.5 MB
EGAF00001168417 cram 966.4 MB
EGAF00001168418 cram 996.0 MB
EGAF00001168419 cram 1.0 GB
EGAF00001168420 cram 805.5 MB
EGAF00001168421 cram 776.7 MB
EGAF00001168422 cram 919.2 MB
EGAF00001168423 cram 850.8 MB
EGAF00001168424 cram 735.5 MB
EGAF00001168425 cram 760.8 MB
EGAF00001168426 cram 881.7 MB
EGAF00001168427 cram 590.9 MB
EGAF00001168428 cram 887.9 MB
EGAF00001168429 cram 717.2 MB
EGAF00001168430 cram 725.3 MB
EGAF00001168431 cram 941.2 MB
EGAF00001168432 cram 971.9 MB
EGAF00001168433 cram 991.1 MB
EGAF00001168434 cram 786.4 MB
EGAF00001168435 cram 759.0 MB
EGAF00001168436 cram 1.2 GB
EGAF00001168437 cram 954.1 MB
EGAF00001170084 cram 935.5 MB
EGAF00001170085 cram 878.1 MB
EGAF00001170086 cram 993.9 MB
EGAF00001170087 cram 880.8 MB
EGAF00001170088 cram 1.2 GB
EGAF00001170089 cram 784.2 MB
EGAF00001170090 cram 928.5 MB
EGAF00001170091 cram 993.4 MB
EGAF00001170092 cram 858.6 MB
EGAF00001170093 cram 829.4 MB
EGAF00001170094 cram 922.6 MB
EGAF00001170095 cram 756.0 MB
EGAF00001170096 cram 1.1 GB
EGAF00001170097 cram 932.3 MB
EGAF00001170098 cram 915.4 MB
EGAF00001170099 cram 858.8 MB
EGAF00001170100 cram 972.3 MB
EGAF00001170101 cram 860.4 MB
EGAF00001170102 cram 1.1 GB
EGAF00001170103 cram 767.8 MB
EGAF00001170104 cram 908.6 MB
EGAF00001170105 cram 970.6 MB
EGAF00001170106 cram 840.2 MB
EGAF00001170107 cram 812.0 MB
EGAF00001170108 cram 903.5 MB
EGAF00001170109 cram 739.0 MB
100 Files (91.0 GB)