Whole genome sequencing of a Grem1 mutant human tumour

Dataset ID Technology Samples
EGAD00001002182 Illumina HiSeq 2000,Illumina HiSeq 2500 2

Dataset Description

The BMP antagonist Grem1 has been shown to be associated with a rare human polyposis
syndrome (HMPS). We have shown that there is a 40KB duplication on chrom 15 found in
some patients with HMPS. Traditional serrated adenomas (rare sporadic polyps) share some
morphological features with HMPS polyps and it has long been hypothesised that they are the
sporadic version of HMPS polyps. We have obtained of one of these
lesions and in this project we aim to characterise this tumour.

Who controls access to this dataset

For each dataset that requires controlled access, there is a corresponding Data Access Committee (DAC) who determine access permissions. Access to actual data files is not managed by the EGA. If you need to request access to this data set, please contact:

Wellcome Trust Sanger Institute
Contact person: Data Sharing
Email: datasharing [at] sanger [dot] ac [dot] uk
Access information:
More details: EGAC00001000205


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