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WGoxBS and SureSelect data of the POPS placenta samples

We carried out whole-genome oxidative bisulfite sequencing (WGoxBS) in the placentas of two healthy female and two healthy male pregnancies generating an average genome depth of coverage of 25x. The sex-specific differential methylation pattern observed in this region was validated in additional 8 healthy placentas (including 2 from the WGoxBS) using SureSelect in-solution target capture. For WGoxBS, placental genomic DNA (4 µg) from 4 healthy pregnancies was processed to achieve 10 kb fragments with the g-Tube (Covaris), according to the manufacturer's instructions. To increase the number of uniquely sequenced reads, two independent libraries were generated for each individual. Multiplexed sequencing was carried out on the Illumina MiSeq, HiSeq 2000, and HiSeq 2500 instruments with 2x100, 2x50 and 2x125 cycles using MiSeq Reagent Kit v3, HiSeq SBS Kit v3 and HiSeq SBS Kit v4, respectively. For SureSelect in-solution capture, placental genomic DNA (3.5 µg) from 8 healthy pregnancies (including 2 from the WGoxBS) was fragmented by the Covaris S220 system according to the SureSelect Methyl-Seq target enrichment protocol (Agilent). All 8 libraries were pooled and sequenced on the Illumina HiSeq 2500 instrument with 2 × 125 cycles using HiSeq SBS Kit v4 and a single lane of the Illumina HiSeq 4000 instrument with 2 × 150 cycles using HiSeq 3000/4000 SBS Kit following Illumina's guidelines (Illumina Application Note: Epigenetics February 2016).

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POPS data access policy

You are not authroised to access POPS data unless you have a written permission from the data access committee which you can contact below: D. Stephen Charnock-Jones. Professor of Reproductive Biology. Department of Obstetrics and Gynaecology. University of Cambridge. The Rosie Hospital, Cambridge. CB2 0SW UK email dscj1@cam.ac.uk Tel +44 1223 336875 Fax +44 1223 215327

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001002205 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00001433440 fq.gz 217.3 MB
EGAF00001433441 fq.gz 235.7 MB
EGAF00001433442 fq.gz 1.5 GB
EGAF00001433443 fq.gz 1.4 GB
EGAF00001433444 fq.gz 1.5 GB
EGAF00001433445 fq.gz 1.4 GB
EGAF00001433446 fq.gz 1.5 GB
EGAF00001433447 fq.gz 1.4 GB
EGAF00001433448 fq.gz 1.5 GB
EGAF00001433449 fq.gz 1.4 GB
EGAF00001433450 fq.gz 1.4 GB
EGAF00001433451 fq.gz 1.4 GB
EGAF00001433452 fq.gz 1.6 GB
EGAF00001433453 fq.gz 1.5 GB
EGAF00001433454 fq.gz 1.5 GB
EGAF00001433455 fq.gz 1.4 GB
EGAF00001433456 fq.gz 1.5 GB
EGAF00001433457 fq.gz 1.4 GB
EGAF00001433458 fq.gz 2.4 GB
EGAF00001433459 fq.gz 2.3 GB
EGAF00001433460 fq.gz 2.3 GB
EGAF00001433461 fq.gz 2.3 GB
EGAF00001433462 fq.gz 2.3 GB
EGAF00001433463 fq.gz 2.3 GB
EGAF00001433464 fq.gz 2.4 GB
EGAF00001433465 fq.gz 2.3 GB
EGAF00001433466 fq.gz 2.3 GB
EGAF00001433467 fq.gz 2.3 GB
EGAF00001433468 fq.gz 2.3 GB
EGAF00001433469 fq.gz 2.3 GB
EGAF00001433470 fq.gz 2.4 GB
EGAF00001433471 fq.gz 2.3 GB
EGAF00001433472 fq.gz 2.3 GB
EGAF00001433473 fq.gz 2.2 GB
EGAF00001433474 fq.gz 322.0 MB
EGAF00001433475 fq.gz 354.9 MB
EGAF00001433476 fq.gz 4.1 GB
EGAF00001433477 fq.gz 4.6 GB
EGAF00001433478 fq.gz 4.2 GB
EGAF00001433479 fq.gz 4.6 GB
EGAF00001433480 fq.gz 4.2 GB
EGAF00001433481 fq.gz 4.6 GB
EGAF00001433482 fq.gz 4.3 GB
EGAF00001433483 fq.gz 4.7 GB
EGAF00001433484 fq.gz 4.3 GB
EGAF00001433485 fq.gz 4.7 GB
EGAF00001433486 fq.gz 4.2 GB
EGAF00001433487 fq.gz 4.6 GB
EGAF00001433488 fq.gz 4.2 GB
EGAF00001433489 fq.gz 4.6 GB
EGAF00001433490 fq.gz 3.9 GB
EGAF00001433491 fq.gz 4.3 GB
EGAF00001433492 fq.gz 318.2 MB
EGAF00001433493 fq.gz 345.3 MB
EGAF00001433494 fq.gz 2.4 GB
EGAF00001433495 fq.gz 2.2 GB
EGAF00001433496 fq.gz 2.4 GB
EGAF00001433497 fq.gz 2.3 GB
EGAF00001433498 fq.gz 2.4 GB
EGAF00001433499 fq.gz 2.2 GB
EGAF00001433500 fq.gz 2.4 GB
EGAF00001433501 fq.gz 2.2 GB
EGAF00001433502 fq.gz 2.3 GB
EGAF00001433503 fq.gz 2.1 GB
EGAF00001433504 fq.gz 2.5 GB
EGAF00001433505 fq.gz 2.4 GB
EGAF00001433506 fq.gz 2.4 GB
EGAF00001433507 fq.gz 2.2 GB
EGAF00001433508 fq.gz 2.3 GB
EGAF00001433509 fq.gz 2.2 GB
EGAF00001433510 fq.gz 4.0 GB
EGAF00001433511 fq.gz 3.9 GB
EGAF00001433512 fq.gz 4.0 GB
EGAF00001433513 fq.gz 3.9 GB
EGAF00001433514 fq.gz 3.9 GB
EGAF00001433515 fq.gz 3.9 GB
EGAF00001433516 fq.gz 4.0 GB
EGAF00001433517 fq.gz 4.0 GB
EGAF00001433518 fq.gz 4.0 GB
EGAF00001433519 fq.gz 3.9 GB
EGAF00001433520 fq.gz 4.0 GB
EGAF00001433521 fq.gz 4.0 GB
EGAF00001433522 fq.gz 4.0 GB
EGAF00001433523 fq.gz 4.0 GB
EGAF00001433524 fq.gz 3.9 GB
EGAF00001433525 fq.gz 3.8 GB
EGAF00001433526 fq.gz 182.3 MB
EGAF00001433527 fq.gz 201.7 MB
EGAF00001433528 fq.gz 2.4 GB
EGAF00001433529 fq.gz 2.7 GB
EGAF00001433530 fq.gz 2.5 GB
EGAF00001433531 fq.gz 2.8 GB
EGAF00001433532 fq.gz 2.5 GB
EGAF00001433533 fq.gz 2.7 GB
EGAF00001433534 fq.gz 2.5 GB
EGAF00001433535 fq.gz 2.8 GB
EGAF00001433536 fq.gz 2.5 GB
EGAF00001433537 fq.gz 2.8 GB
EGAF00001433538 fq.gz 2.5 GB
EGAF00001433539 fq.gz 2.7 GB
EGAF00001433540 fq.gz 2.5 GB
EGAF00001433541 fq.gz 2.8 GB
EGAF00001433542 fq.gz 2.3 GB
EGAF00001433543 fq.gz 2.5 GB
EGAF00001433544 fq.gz 1.7 GB
EGAF00001433545 fq.gz 1.8 GB
EGAF00001433546 fq.gz 2.5 GB
EGAF00001433547 fq.gz 2.9 GB
EGAF00001433548 fq.gz 4.3 GB
EGAF00001433549 fq.gz 4.1 GB
EGAF00001433550 fq.gz 4.3 GB
EGAF00001433551 fq.gz 4.1 GB
EGAF00001433552 fq.gz 4.3 GB
EGAF00001433553 fq.gz 4.2 GB
EGAF00001433554 fq.gz 4.2 GB
EGAF00001433555 fq.gz 4.0 GB
EGAF00001433556 fq.gz 4.3 GB
EGAF00001433557 fq.gz 4.1 GB
EGAF00001433558 fq.gz 4.3 GB
EGAF00001433559 fq.gz 4.1 GB
EGAF00001433560 fq.gz 4.3 GB
EGAF00001433561 fq.gz 4.1 GB
EGAF00001433562 fq.gz 3.8 GB
EGAF00001433563 fq.gz 3.6 GB
EGAF00001433564 fq.gz 4.4 GB
EGAF00001433565 fq.gz 4.2 GB
EGAF00001433566 fq.gz 4.5 GB
EGAF00001433567 fq.gz 4.3 GB
EGAF00001433568 fq.gz 400.5 MB
EGAF00001433569 fq.gz 429.3 MB
EGAF00001433570 fq.gz 6.3 GB
EGAF00001433571 fq.gz 6.6 GB
EGAF00001433572 fq.gz 6.2 GB
EGAF00001433573 fq.gz 6.5 GB
EGAF00001433574 fq.gz 6.1 GB
EGAF00001433575 fq.gz 6.4 GB
EGAF00001433576 fq.gz 6.3 GB
EGAF00001433577 fq.gz 6.5 GB
EGAF00001433578 fq.gz 6.3 GB
EGAF00001433579 fq.gz 6.4 GB
EGAF00001433580 fq.gz 6.3 GB
EGAF00001433581 fq.gz 6.5 GB
EGAF00001433582 fq.gz 6.4 GB
EGAF00001433583 fq.gz 6.5 GB
EGAF00001433584 fq.gz 5.4 GB
EGAF00001433585 fq.gz 5.5 GB
EGAF00001433586 fq.gz 1.3 GB
EGAF00001433587 fq.gz 1.4 GB
EGAF00001433588 fq.gz 1.8 GB
EGAF00001433589 fq.gz 2.0 GB
EGAF00001433590 fq.gz 165.1 MB
EGAF00001433591 fq.gz 179.5 MB
EGAF00001433592 fq.gz 1.2 GB
EGAF00001433593 fq.gz 1.2 GB
EGAF00001433594 fq.gz 1.3 GB
EGAF00001433595 fq.gz 1.2 GB
EGAF00001433596 fq.gz 1.2 GB
EGAF00001433597 fq.gz 1.2 GB
EGAF00001433598 fq.gz 1.2 GB
EGAF00001433599 fq.gz 1.2 GB
EGAF00001433600 fq.gz 1.2 GB
EGAF00001433601 fq.gz 1.1 GB
EGAF00001433602 fq.gz 1.3 GB
EGAF00001433603 fq.gz 1.2 GB
EGAF00001433604 fq.gz 1.2 GB
EGAF00001433605 fq.gz 1.2 GB
EGAF00001433606 fq.gz 1.2 GB
EGAF00001433607 fq.gz 1.1 GB
EGAF00001433608 fq.gz 2.0 GB
EGAF00001433609 fq.gz 2.0 GB
EGAF00001433610 fq.gz 2.0 GB
EGAF00001433611 fq.gz 2.0 GB
EGAF00001433612 fq.gz 2.0 GB
EGAF00001433613 fq.gz 1.9 GB
EGAF00001433614 fq.gz 2.0 GB
EGAF00001433615 fq.gz 2.0 GB
EGAF00001433616 fq.gz 2.0 GB
EGAF00001433617 fq.gz 2.0 GB
EGAF00001433618 fq.gz 2.0 GB
EGAF00001433619 fq.gz 2.0 GB
EGAF00001433620 fq.gz 2.0 GB
EGAF00001433621 fq.gz 2.0 GB
EGAF00001433622 fq.gz 2.0 GB
EGAF00001433623 fq.gz 1.9 GB
EGAF00001433624 fq.gz 246.6 MB
EGAF00001433625 fq.gz 271.9 MB
EGAF00001433626 fq.gz 3.3 GB
EGAF00001433627 fq.gz 3.7 GB
EGAF00001433628 fq.gz 3.3 GB
EGAF00001433629 fq.gz 3.7 GB
EGAF00001433630 fq.gz 3.3 GB
EGAF00001433631 fq.gz 3.7 GB
EGAF00001433632 fq.gz 3.4 GB
EGAF00001433633 fq.gz 3.8 GB
EGAF00001433634 fq.gz 3.4 GB
EGAF00001433635 fq.gz 3.8 GB
EGAF00001433636 fq.gz 3.3 GB
EGAF00001433637 fq.gz 3.7 GB
EGAF00001433638 fq.gz 3.3 GB
EGAF00001433639 fq.gz 3.7 GB
EGAF00001433640 fq.gz 3.1 GB
EGAF00001433641 fq.gz 3.5 GB
EGAF00001433767 fq.gz 685.0 MB
EGAF00001433768 fq.gz 727.3 MB
EGAF00001433769 fq.gz 775.4 MB
EGAF00001433770 fq.gz 905.0 MB
EGAF00001433771 fq.gz 889.1 MB
EGAF00001433772 fq.gz 945.1 MB
EGAF00001433773 fq.gz 1.2 GB
EGAF00001433774 fq.gz 1.4 GB
EGAF00001433775 fq.gz 1.1 GB
EGAF00001433776 fq.gz 1.1 GB
EGAF00001433777 fq.gz 1.3 GB
EGAF00001433778 fq.gz 1.5 GB
EGAF00001433779 fq.gz 693.3 MB
EGAF00001433780 fq.gz 745.2 MB
EGAF00001433781 fq.gz 955.7 MB
EGAF00001433782 fq.gz 1.1 GB
EGAF00001433783 fq.gz 1.1 GB
EGAF00001433784 fq.gz 1.2 GB
EGAF00001433785 fq.gz 1.6 GB
EGAF00001433786 fq.gz 1.8 GB
EGAF00001433787 fq.gz 940.0 MB
EGAF00001433788 fq.gz 1.0 GB
EGAF00001433789 fq.gz 1.2 GB
EGAF00001433790 fq.gz 1.4 GB
EGAF00001433791 bam 79.5 GB
EGAF00001433792 bam 88.2 GB
EGAF00001433793 bam 64.3 GB
EGAF00001433794 bam 75.0 GB
EGAF00001433795 bam 9.3 GB
EGAF00001433796 bam 3.4 GB
EGAF00001433797 bam 6.9 GB
EGAF00001433798 bam 4.7 GB
EGAF00001433799 bam 5.3 GB
EGAF00001433800 bam 3.8 GB
EGAF00001433801 bam 6.3 GB
EGAF00001433802 bam 4.8 GB
238 Files (960.2 GB)