Amplicon-based sequencing of drug resistant lung cancer cell lines (2017-07-05)
A EGFR mutant NSCLC cell line which is sensitive to AZD9291 inhibition was mutagenised with the chemical mutagen ENU and then drug selected using a AZD9291. Single cell derived colonies were then manually picked and expanded in drug. Resistance was confirmed in a 14 day assay and DNA was collected. These then underwent targeted amplicon-based sequencing to confirm candidate resistance effectors hypothesised from currently available literature. This dataset contains all the data available for this study on 2017-07-05.
- 11/07/2017
- 177 samples
- DAC: EGAC00001000000
- Technology: Illumina MiSeq
DUO:0000019 version: 2021-02-23
publication required
This data use modifier indicates that requestor agrees to make results of studies using the data available to the larger scientific community.
DUO:0000026 version: 2021-02-23
user specific restriction
This data use modifier indicates that use is limited to use by approved users.
DUO:0000028 version: 2021-02-23
institution specific restriction
This data use modifier indicates that use is limited to use within an approved institution.
DUO:0000042 version: 2021-02-23
general research use
This data use permission indicates that use is allowed for general research use for any research purpose.
Wellcome Trust Sanger Institute Cancer Genome Group Data Sharing Policy
Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.
| Study ID | Study Title | Study Type |
|---|---|---|
| EGAS00001001675 | Cancer Genomics |
This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.
| ID | File Type | Size | Quality Report |
Located in
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|---|---|---|---|---|
| EGAF00001305538 | cram | 9.9 MB | Report |
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| EGAF00001305539 | cram | 10.3 MB | Report |
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| EGAF00001305540 | cram | 10.5 MB | Report |
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| EGAF00001305541 | cram | 10.7 MB | Report |
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| EGAF00001305542 | cram | 12.0 MB | Report |
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| EGAF00001305543 | cram | 5.1 MB | Report |
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| EGAF00001305544 | cram | 2.5 MB | Report |
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| EGAF00001305545 | cram | 17.6 MB | Report |
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| EGAF00001305546 | cram | 1.9 MB | Report |
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| EGAF00001305547 | cram | 7.8 MB | Report |
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| EGAF00001305548 | cram | 3.0 MB | Report |
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| EGAF00001305549 | cram | 12.0 MB | Report |
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| EGAF00001305550 | cram | 7.2 MB | Report |
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| EGAF00001305551 | cram | 11.5 MB | Report |
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| EGAF00001305552 | cram | 7.3 MB | Report |
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| EGAF00001305553 | cram | 2.7 MB | Report |
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| EGAF00001305554 | cram | 13.4 MB | Report |
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| EGAF00001305555 | cram | 11.0 MB | Report |
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| EGAF00001305556 | cram | 7.7 MB | Report |
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| EGAF00001305557 | cram | 11.3 MB | Report |
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| EGAF00001305558 | cram | 2.6 MB | Report |
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| EGAF00001305559 | cram | 7.4 MB | Report |
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| EGAF00001305560 | cram | 8.2 MB | Report |
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| EGAF00001305561 | cram | 11.9 MB | Report |
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| EGAF00001305562 | cram | 7.8 MB | Report |
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| EGAF00001306435 | cram | 9.3 MB | Report |
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| EGAF00001306436 | cram | 6.0 MB | Report |
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| EGAF00001306437 | cram | 14.4 MB | Report |
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| EGAF00001306438 | cram | 7.6 MB | Report |
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| EGAF00001306439 | cram | 7.7 MB | Report |
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| EGAF00001306440 | cram | 9.2 MB | Report |
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| EGAF00001306441 | cram | 7.4 MB | Report |
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| EGAF00001306442 | cram | 11.1 MB | Report |
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| EGAF00001306443 | cram | 15.1 MB | Report |
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| EGAF00001306444 | cram | 3.5 MB | Report |
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| EGAF00001306445 | cram | 15.1 MB | Report |
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| EGAF00001306446 | cram | 3.4 MB | Report |
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| EGAF00001306447 | cram | 10.5 MB | Report |
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| EGAF00001306448 | cram | 10.5 MB | Report |
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| EGAF00001306449 | cram | 11.2 MB | Report |
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| EGAF00001306450 | cram | 6.0 MB | Report |
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| EGAF00001306451 | cram | 2.8 MB | Report |
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| EGAF00001306452 | cram | 3.9 MB | Report |
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| EGAF00001306453 | cram | 3.2 MB | Report |
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| EGAF00001306454 | cram | 3.3 MB | Report |
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| EGAF00001306455 | cram | 3.7 MB | Report |
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| EGAF00001306456 | cram | 4.2 MB | Report |
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| EGAF00001306457 | cram | 6.8 MB | Report |
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| EGAF00001306458 | cram | 4.4 MB | Report |
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| EGAF00001306459 | cram | 4.1 MB | Report |
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| EGAF00001306460 | cram | 4.2 MB | Report |
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| EGAF00001306461 | cram | 3.6 MB | Report |
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| EGAF00001306462 | cram | 3.8 MB | Report |
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| EGAF00001306463 | cram | 4.0 MB | Report |
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| EGAF00001306464 | cram | 4.0 MB | Report |
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| EGAF00001306465 | cram | 3.1 MB | Report |
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| EGAF00001306466 | cram | 3.5 MB | Report |
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| EGAF00001306467 | cram | 4.4 MB | Report |
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| EGAF00001306468 | cram | 2.7 MB | Report |
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| EGAF00001306469 | cram | 4.2 MB | Report |
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| EGAF00001306470 | cram | 3.7 MB | Report |
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| EGAF00001306471 | cram | 4.4 MB | Report |
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| EGAF00001306472 | cram | 3.6 MB | Report |
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| EGAF00001306473 | cram | 2.7 MB | Report |
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| EGAF00001306474 | cram | 991.3 kB | Report |
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| EGAF00001306475 | cram | 2.9 MB | Report |
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| EGAF00001306476 | cram | 3.5 MB | Report |
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| EGAF00001306477 | cram | 4.6 MB | Report |
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| EGAF00001306478 | cram | 2.4 MB | Report |
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| EGAF00001306479 | cram | 3.0 MB | Report |
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| EGAF00001306480 | cram | 3.0 MB | Report |
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| EGAF00001306481 | cram | 3.0 MB | Report |
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| EGAF00001306482 | cram | 4.3 MB | Report |
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| EGAF00001306483 | cram | 4.1 MB | Report |
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| EGAF00001306484 | cram | 4.7 MB | Report |
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| EGAF00001306485 | cram | 5.7 MB | Report |
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| EGAF00001306486 | cram | 3.9 MB | Report |
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| EGAF00001306487 | cram | 3.4 MB | Report |
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| EGAF00001306488 | cram | 4.8 MB | Report |
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| EGAF00001306489 | cram | 4.2 MB | Report |
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| EGAF00001306490 | cram | 5.5 MB | Report |
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| EGAF00001306491 | cram | 3.8 MB | Report |
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| EGAF00001306492 | cram | 3.3 MB | Report |
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| EGAF00001306493 | cram | 4.9 MB | Report |
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| EGAF00001306494 | cram | 3.9 MB | Report |
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| EGAF00001306495 | cram | 3.7 MB | Report |
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| EGAF00001306496 | cram | 4.6 MB | Report |
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| EGAF00001306497 | cram | 4.9 MB | Report |
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| EGAF00001306498 | cram | 6.0 MB | Report |
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| EGAF00001306499 | cram | 598.2 kB | Report |
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| EGAF00001306500 | cram | 4.4 MB | Report |
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| EGAF00001306501 | cram | 4.5 MB | Report |
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| EGAF00001306502 | cram | 6.1 MB | Report |
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| EGAF00001306503 | cram | 8.2 MB | Report |
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| EGAF00001306504 | cram | 6.2 MB | Report |
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| EGAF00001306505 | cram | 4.4 MB | Report |
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| EGAF00001306506 | cram | 22.4 MB | Report |
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| EGAF00001306507 | cram | 5.3 MB | Report |
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| EGAF00001306508 | cram | 3.0 MB | Report |
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| EGAF00001306509 | cram | 2.1 MB | Report |
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| EGAF00001306510 | cram | 3.6 MB | Report |
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| EGAF00001306511 | cram | 2.8 MB | Report |
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| EGAF00001306512 | cram | 5.7 MB | Report |
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| EGAF00001306513 | cram | 12.2 MB | Report |
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| EGAF00001306514 | cram | 564.3 kB | Report |
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| EGAF00001306515 | cram | 1.7 MB | Report |
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| EGAF00001306516 | cram | 10.3 MB | Report |
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| EGAF00001306517 | cram | 4.2 MB | Report |
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| EGAF00001306518 | cram | 1.2 MB | Report |
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| EGAF00001306519 | cram | 2.0 MB | Report |
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| EGAF00001306520 | cram | 3.0 MB | Report |
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| EGAF00001306521 | cram | 21.0 MB | Report |
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| EGAF00001306522 | cram | 4.2 MB | Report |
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| EGAF00001306523 | cram | 18.1 MB | Report |
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| EGAF00001306524 | cram | 6.8 MB | Report |
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| EGAF00001306525 | cram | 7.2 MB | Report |
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| EGAF00001306526 | cram | 688.7 kB | Report |
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| EGAF00001306527 | cram | 14.9 MB | Report |
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| EGAF00001306528 | cram | 14.9 MB | Report |
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| EGAF00001307313 | cram | 12.2 MB | Report |
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| EGAF00001307314 | cram | 23.4 MB | Report |
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| EGAF00001307315 | cram | 15.7 MB | Report |
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| EGAF00001307316 | cram | 4.5 MB | Report |
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| EGAF00001307317 | cram | 11.4 MB | Report |
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| EGAF00001307318 | cram | 11.6 MB | Report |
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| EGAF00001307319 | cram | 2.1 MB | Report |
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| EGAF00001307320 | cram | 8.1 MB | Report |
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| EGAF00001307321 | cram | 18.6 MB | Report |
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| EGAF00001307322 | cram | 18.6 MB | Report |
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| EGAF00001307323 | cram | 12.1 MB | Report |
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| EGAF00001307324 | cram | 2.6 MB | Report |
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| EGAF00001307325 | cram | 9.9 MB | Report |
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| EGAF00001307326 | cram | 10.9 MB | Report |
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| EGAF00001307327 | cram | 22.2 MB | Report |
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| EGAF00001307328 | cram | 8.3 MB | Report |
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| EGAF00001307329 | cram | 3.5 MB | Report |
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| EGAF00001307330 | cram | 22.4 MB | Report |
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| EGAF00001307331 | cram | 7.4 MB | Report |
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| EGAF00001307332 | cram | 6.3 MB | Report |
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| EGAF00001307333 | cram | 884.3 kB | Report |
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| EGAF00001307334 | cram | 2.2 MB | Report |
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| EGAF00001307335 | cram | 4.1 MB | Report |
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| EGAF00001307336 | cram | 3.4 MB | Report |
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| EGAF00001307337 | cram | 4.0 MB | Report |
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| EGAF00001307338 | cram | 7.4 MB | Report |
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| EGAF00001307339 | cram | 2.6 MB | Report |
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| EGAF00001307340 | cram | 3.9 MB | Report |
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| EGAF00001307341 | cram | 3.3 MB | Report |
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| EGAF00001307342 | cram | 3.2 MB | Report |
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| EGAF00001307343 | cram | 3.4 MB | Report |
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| EGAF00001307344 | cram | 6.5 MB | Report |
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| EGAF00001307345 | cram | 7.9 MB | Report |
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| EGAF00001307346 | cram | 7.8 MB | Report |
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| EGAF00001307347 | cram | 3.3 MB | Report |
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| EGAF00001307348 | cram | 4.4 MB | Report |
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| EGAF00001307349 | cram | 3.5 MB | Report |
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| EGAF00001307350 | cram | 2.3 MB | Report |
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| EGAF00001307351 | cram | 3.2 MB | Report |
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| EGAF00001307352 | cram | 813.7 kB | Report |
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| EGAF00001307353 | cram | 20.2 MB | Report |
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| EGAF00001307354 | cram | 4.5 MB | Report |
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| EGAF00001307355 | cram | 2.1 MB | Report |
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| EGAF00001307356 | cram | 2.1 MB | Report |
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| EGAF00001307357 | cram | 2.7 MB | Report |
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| EGAF00001307358 | cram | 2.6 MB | Report |
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| EGAF00001307359 | cram | 4.0 MB | Report |
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| EGAF00001307360 | cram | 2.5 MB | Report |
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| EGAF00001307361 | cram | 4.4 MB | Report |
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| EGAF00001307362 | cram | 4.8 MB | Report |
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| EGAF00001307363 | cram | 8.1 MB | Report |
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| EGAF00001307364 | cram | 3.4 MB | Report |
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| EGAF00001307365 | cram | 3.7 MB | Report |
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| EGAF00001307366 | cram | 8.4 MB | Report |
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| EGAF00001307367 | cram | 4.1 MB | Report |
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| EGAF00001590352 | cram | 32.5 MB | Report |
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| EGAF00001590353 | cram | 18.6 MB | Report |
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| EGAF00001590354 | cram | 5.0 MB | Report |
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| 177 Files (1.2 GB) | ||||