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Tam-seq of tumor samples for HGSOC copy-number signatures study

This dataset contains targeted amplicon sequencing of DNA extracted from 300 samples of 142 patients (158 methanol-fixed relapse biopsies and 142 FFPE archival diagnostic tissues). Samples were sequenced on Illumina HiSeq 2500 and were aligned to human genome assembly GRCh37 (hg19)to produce 600 bam files (2 technical replicates per sample).

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The UK Translational Research in Ovarian Cancer (BriTROC) Consortium Data Access and Use Agreement for non personal data.

Between Ovarian Cancer Action, a company limited by guarantee (registered in England and Wales under number 5403443) and a charity (registered in England under number 1109743 and registered in Scotland under number SC043478) of 8 – 12 Camden High St, London NW1 0JH, and Cancer Research UK, a company limited by guarantee (registered in England and Wales under number 4325234) and a charity (registered in England under number 1089464 and registered in Scotland under number SC041666) of Angel Building, 407 St John Street, London, EC1V 4AD, United Kingdom (collectively referred to as the “Funders”), and the undersigned parties. This agreement governs the terms on which access will be granted to the genotype and expression data generated as a result of the activities of the BriTROC Consortium and deposited by members of the Consortium including the Funders. In signing this agreement, you are agreeing with the Funders to be bound by the terms and conditions set out in this agreement. NOW THEREFORE in consideration of the access to the Data provided by the Funders to User Institution, and for other good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, and intending to be legally bound hereby, the parties hereto agree as follows: Definitions: “Application” means an application made by an entity (including You) to request access to the Data for a specific project and/or purpose. “Consortium” means the UK Translational Research in Ovarian Cancer consortium, known as BriTROC. “Data Access Committee” means the committee established by BriTROC to consider Applications. “Data” means non personal data including all and any human genetic and raw expression data obtained from the Consortium (which is currently available through the European Genome-phenome Archive). “Data Subject” means a person, who has been informed of the purpose for which the Data was collected, is currently held, and the purposes for which it can and will be distributed and disclosed, and has given his/her informed consent thereto. All references to individual Data Subjects have been removed and the Data is no longer personal data. User means a researcher whose User Institution has signed this Data Access Agreement and has received acknowledgement of the acceptance of its Application. Publications means, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. User Institution means the organisation at which the User is employed, affiliated or enrolled. User Institution is referred to within this Agreement as “You” (and “Your” shall be construed accordingly). Terms and Conditions: 1. You agree to preserve, at all times, the confidentiality and privacy of information and Data pertaining to Data Subjects. In particular, you undertake not to use, or attempt to use the Data to compromise or otherwise breach or infringe the confidentiality and privacy of information on Data Subjects. 
2. You agree not to attempt to link the Data to any other data source on the same samples, link the Data to any person or otherwise identify any Data Subject from the Data. We have taken organisational and technical measures to ensure this cannot happen. 
3. You agree not to transfer or disclose the Data, in whole or part, to others, except to persons within the User Institution for the fulfilment of the Purpose as reasonably necessary for Data/safety monitoring or programme management. If you wish to disclose the Data to a collaborator outside the User Institution, the third party must make a separate Application for access to the Data and enter into a separate Agreement. 
4. You agree to use the Data for the advancement of medical research, and solely for the approved purpose and project described in Your Application and for no other purpose, which is attached hereto as Schedule “B” (the “Purpose”); provided that any use of the Data beyond the scope of the Purpose will require a new Application, approval and Agreement. You agree to destroy the raw data once the project is completed, and upon request of the Consortium, provide written certification of such destruction. 
5. You agree that Data may be reissued from time to time, with suitable versioning. If the reissue is at the request of sample donors and/or other ethical scrutiny, you will destroy earlier versions of the Data, and upon request of the Consortium, provide written certification of such destruction. 
6. You agree to acknowledge in any work or Publications based in whole or part on the Data, the published paper from which the Data derives, the version of the Data, and the role of the Consortium and the Funders, in accordance with the Publications Policy attached as Schedule “A”. 
7. You agree and acknowledge that the Consortium, its members, the original Data creators, depositors or copyright holders, or the Funders: 
a) bear no legal responsibility or liability for the accuracy or comprehensiveness of the Data, or from any use of the Data including further analysis or interpretation of such Data; and
b) shall have no liability for any direct or indirect, consequential, or incidental damages or losses whatsoever arising out of Your use of the Data, or from the unavailability of, or lack of access to, the Data for whatever reason; and 
c) disclaim any and all representations, conditions or warranties (either express, implied or statutory) regarding the Data, including accuracy of the Data or that the Data corresponds with a particular description or is fit for a particular purpose. 
8. You shall indemnify, hold harmless and defend each of the Funders, any members of the Consortium and their respective directors, officers, employees and agents against any and all claims (including all associated legal fees and disbursements actually incurred) arising out of this Agreement, including without limitation against any damages or losses, consequential or otherwise, arising in any manner at all from or out of Your use of the Data. Section 8 shall not apply to any public body or institution that is prevented by applicable laws from providing indemnification. 9. You understand and acknowledge that the Data is owned by the Funders and protected by copyright, database rights and other intellectual property rights owned by the Funders. You agree that you shall not reproduce or copy the Data, except as reasonably required to carry out the Purpose and for no other purpose, or sell all or any part of the Data in any circumstances. 
10. You recognise that nothing in this Agreement shall operate to transfer to You any ownership or intellectual property rights relating to the Data. 
11. You accept that this Agreement will terminate immediately upon any breach of this Agreement by You and You will be required to destroy or return any Data, and upon request, provide written certification of such destruction. For the avoidance of doubt clause 3, 7, 8, 14, 15 will continue to operate in full force and effect. 
12. You accept that it may be necessary for the Funders to alter the terms of this Agreement from time to time in order to address new concerns. In this event, one of the Funders or a representative of the Consortium will contact You to inform You of any changes and You agree that Your continued use of the Data shall be dependent on the parties entering into a new version of the Agreement. 
13. You agree that you will submit a report to the Consortium Data Access Committee, if requested, on completion of the Purpose. The Consortium Data Access Committee agrees to treat the report and all information, data, results, and conclusions contained within such report as confidential information belonging to the User Institution. 
14. You agree that the Data is protected by and subject to applicable international laws, which may include without limitation the UK Data Protection Act 1998 and that you are responsible for ensuring compliance with any such laws. The Funders (via the BriTROC Data Access Committee) reserve the right to request and inspect Your data security and management documentation to ensure the adequacy of data protection measures in countries that have no privacy legislation comparable with that contained herein. 
15. Part or all of any section of this Agreement that is indefinite, invalid, illegal or otherwise voidable or unenforceable may be severed and the balance of this agreement will continue in full force and effect. 
Schedule “A” Publications Policy Any use of Data must acknowledge BriTROC using the following wording: "This study makes use of data generated by the BriTROC consortium. Funding for the project was provided by Ovraian Cancer Action and Cancer Research UK." and cite the relevant primary BRITROC publications (Piskorz, Ennis, Macintyre et al, Ann. Oncol 2015) which is the source of the Data. Schedule “B”
Application form (approved by the Consortium Data Access Committee)

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001002557 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00002034436 bam 70.0 MB
EGAF00002034437 bam 80.1 MB
EGAF00002034438 bam 78.1 MB
EGAF00002034439 bam 37.1 MB
EGAF00002034440 bam 81.4 MB
EGAF00002034441 bam 91.7 MB
EGAF00002034442 bam 49.2 MB
EGAF00002034443 bam 47.4 MB
EGAF00002034444 bam 52.7 MB
EGAF00002034445 bam 49.3 MB
EGAF00002034446 bam 37.8 MB
EGAF00002034447 bam 33.2 MB
EGAF00002034448 bam 66.6 MB
EGAF00002034449 bam 51.1 MB
EGAF00002034450 bam 69.9 MB
EGAF00002034451 bam 64.1 MB
EGAF00002034452 bam 54.8 MB
EGAF00002034453 bam 64.9 MB
EGAF00002034454 bam 44.3 MB
EGAF00002034455 bam 48.2 MB
EGAF00002034456 bam 45.2 MB
EGAF00002034457 bam 75.7 MB
EGAF00002034458 bam 74.6 MB
EGAF00002034459 bam 6.0 MB
EGAF00002034460 bam 7.2 MB
EGAF00002034461 bam 7.3 MB
EGAF00002034462 bam 6.9 MB
EGAF00002034463 bam 7.0 MB
EGAF00002034464 bam 7.4 MB
EGAF00002034465 bam 7.1 MB
EGAF00002034466 bam 10.1 MB
EGAF00002034467 bam 7.4 MB
EGAF00002034468 bam 7.9 MB
EGAF00002034469 bam 9.5 MB
EGAF00002034470 bam 6.5 MB
EGAF00002034471 bam 3.9 MB
EGAF00002034472 bam 5.5 MB
EGAF00002034473 bam 7.9 MB
EGAF00002034474 bam 8.3 MB
EGAF00002034475 bam 12.6 MB
EGAF00002034476 bam 8.0 MB
EGAF00002034477 bam 10.9 MB
EGAF00002034478 bam 6.7 MB
EGAF00002034479 bam 11.8 MB
EGAF00002034480 bam 12.8 MB
EGAF00002034481 bam 14.1 MB
EGAF00002034505 bam 61.1 MB
EGAF00002034506 bam 50.7 MB
EGAF00002034507 bam 67.3 MB
EGAF00002034508 bam 69.2 MB
EGAF00002034509 bam 62.1 MB
EGAF00002034510 bam 73.8 MB
EGAF00002034511 bam 64.8 MB
EGAF00002034512 bam 51.7 MB
EGAF00002034513 bam 50.1 MB
EGAF00002034514 bam 58.8 MB
EGAF00002034515 bam 74.4 MB
EGAF00002034516 bam 62.0 MB
EGAF00002034517 bam 67.3 MB
EGAF00002034518 bam 74.9 MB
EGAF00002034519 bam 66.9 MB
EGAF00002034520 bam 64.8 MB
EGAF00002034521 bam 72.8 MB
EGAF00002034522 bam 86.5 MB
EGAF00002034523 bam 79.9 MB
EGAF00002034524 bam 63.4 MB
EGAF00002034525 bam 68.3 MB
EGAF00002034526 bam 67.7 MB
EGAF00002034527 bam 78.0 MB
EGAF00002034528 bam 17.9 MB
EGAF00002034529 bam 13.4 MB
EGAF00002034530 bam 13.3 MB
EGAF00002034531 bam 13.1 MB
EGAF00002034532 bam 13.7 MB
EGAF00002034533 bam 13.8 MB
EGAF00002034534 bam 12.9 MB
EGAF00002034535 bam 16.7 MB
EGAF00002034536 bam 14.5 MB
EGAF00002034537 bam 11.5 MB
EGAF00002034538 bam 11.7 MB
EGAF00002034539 bam 10.9 MB
EGAF00002034540 bam 18.7 MB
EGAF00002034541 bam 20.2 MB
EGAF00002034542 bam 20.1 MB
EGAF00002034543 bam 20.4 MB
EGAF00002034544 bam 18.6 MB
EGAF00002034545 bam 19.2 MB
EGAF00002034546 bam 18.8 MB
EGAF00002034547 bam 21.4 MB
EGAF00002034548 bam 19.6 MB
EGAF00002034549 bam 16.7 MB
EGAF00002034550 bam 18.7 MB
EGAF00002034574 bam 75.9 MB
EGAF00002034575 bam 57.4 MB
EGAF00002034576 bam 42.2 MB
EGAF00002034577 bam 46.5 MB
EGAF00002034578 bam 49.4 MB
EGAF00002034579 bam 56.1 MB
EGAF00002034580 bam 72.0 MB
EGAF00002034581 bam 81.9 MB
EGAF00002034582 bam 40.9 MB
EGAF00002034583 bam 55.3 MB
EGAF00002034584 bam 28.3 MB
EGAF00002034585 bam 27.5 MB
EGAF00002034586 bam 26.4 MB
EGAF00002034587 bam 54.6 MB
EGAF00002034588 bam 45.6 MB
EGAF00002034589 bam 54.7 MB
EGAF00002034590 bam 62.9 MB
EGAF00002034591 bam 59.5 MB
EGAF00002034592 bam 59.9 MB
EGAF00002034593 bam 29.3 MB
EGAF00002034594 bam 78.2 MB
EGAF00002034595 bam 15.0 MB
EGAF00002034596 bam 65.8 MB
EGAF00002034597 bam 19.7 MB
EGAF00002034598 bam 25.0 MB
EGAF00002034599 bam 18.0 MB
EGAF00002034600 bam 19.8 MB
EGAF00002034601 bam 19.9 MB
EGAF00002034602 bam 21.4 MB
EGAF00002034603 bam 23.4 MB
EGAF00002034604 bam 21.3 MB
EGAF00002034605 bam 17.9 MB
EGAF00002034606 bam 21.5 MB
EGAF00002034607 bam 19.2 MB
EGAF00002034608 bam 21.3 MB
EGAF00002034609 bam 20.9 MB
EGAF00002034610 bam 5.1 MB
EGAF00002034611 bam 5.5 MB
EGAF00002034612 bam 4.7 MB
EGAF00002034613 bam 4.5 MB
EGAF00002034614 bam 6.6 MB
EGAF00002034615 bam 5.7 MB
EGAF00002034616 bam 6.4 MB
EGAF00002034617 bam 6.2 MB
EGAF00002034618 bam 5.9 MB
EGAF00002034619 bam 5.9 MB
EGAF00002034643 bam 41.0 MB
EGAF00002034644 bam 53.9 MB
EGAF00002034645 bam 73.7 MB
EGAF00002034646 bam 79.0 MB
EGAF00002034647 bam 37.3 MB
EGAF00002034648 bam 45.4 MB
EGAF00002034649 bam 66.7 MB
EGAF00002034650 bam 45.0 MB
EGAF00002034651 bam 72.7 MB
EGAF00002034652 bam 56.5 MB
EGAF00002034653 bam 70.0 MB
EGAF00002034654 bam 54.8 MB
EGAF00002034655 bam 52.3 MB
EGAF00002034656 bam 47.7 MB
EGAF00002034657 bam 62.8 MB
EGAF00002034658 bam 27.0 MB
EGAF00002034659 bam 65.6 MB
EGAF00002034660 bam 62.7 MB
EGAF00002034661 bam 67.2 MB
EGAF00002034662 bam 50.4 MB
EGAF00002034663 bam 35.7 MB
EGAF00002034664 bam 38.6 MB
EGAF00002034665 bam 36.4 MB
EGAF00002034666 bam 5.5 MB
EGAF00002034667 bam 22.0 MB
EGAF00002034668 bam 21.8 MB
EGAF00002034669 bam 8.5 MB
EGAF00002034670 bam 18.9 MB
EGAF00002034671 bam 6.4 MB
EGAF00002034672 bam 5.6 MB
EGAF00002034673 bam 5.2 MB
EGAF00002034674 bam 4.2 MB
EGAF00002034675 bam 5.4 MB
EGAF00002034676 bam 7.1 MB
EGAF00002034677 bam 5.5 MB
EGAF00002034678 bam 5.7 MB
EGAF00002034679 bam 6.9 MB
EGAF00002034680 bam 4.3 MB
EGAF00002034681 bam 4.7 MB
EGAF00002034682 bam 4.5 MB
EGAF00002034683 bam 4.1 MB
EGAF00002034684 bam 5.4 MB
EGAF00002034685 bam 5.3 MB
EGAF00002034686 bam 5.2 MB
EGAF00002034687 bam 5.3 MB
EGAF00002034688 bam 4.9 MB
EGAF00002034712 bam 60.7 MB
EGAF00002034713 bam 58.1 MB
EGAF00002034714 bam 34.8 MB
EGAF00002034715 bam 37.2 MB
EGAF00002034716 bam 41.7 MB
EGAF00002034717 bam 33.0 MB
EGAF00002034718 bam 37.0 MB
EGAF00002034719 bam 36.1 MB
EGAF00002034720 bam 33.4 MB
EGAF00002034721 bam 31.8 MB
EGAF00002034722 bam 31.0 MB
EGAF00002034723 bam 67.5 MB
EGAF00002034724 bam 62.1 MB
EGAF00002034725 bam 78.5 MB
EGAF00002034726 bam 52.3 MB
EGAF00002034727 bam 37.1 MB
EGAF00002034728 bam 45.3 MB
EGAF00002034729 bam 51.2 MB
EGAF00002034730 bam 51.2 MB
EGAF00002034731 bam 40.4 MB
EGAF00002034732 bam 62.5 MB
EGAF00002034733 bam 54.3 MB
EGAF00002034734 bam 50.9 MB
EGAF00002034735 bam 4.4 MB
EGAF00002034736 bam 4.9 MB
EGAF00002034737 bam 7.8 MB
EGAF00002034738 bam 5.9 MB
EGAF00002034739 bam 5.5 MB
EGAF00002034740 bam 5.6 MB
EGAF00002034741 bam 4.9 MB
EGAF00002034742 bam 6.2 MB
EGAF00002034743 bam 3.9 MB
EGAF00002034744 bam 6.9 MB
EGAF00002034745 bam 6.8 MB
EGAF00002034746 bam 5.1 MB
EGAF00002034747 bam 4.5 MB
EGAF00002034748 bam 5.0 MB
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EGAF00002034750 bam 4.5 MB
EGAF00002034751 bam 7.4 MB
EGAF00002034752 bam 10.3 MB
EGAF00002034753 bam 5.0 MB
EGAF00002034754 bam 5.2 MB
EGAF00002034755 bam 4.5 MB
EGAF00002034756 bam 4.6 MB
EGAF00002034757 bam 5.4 MB
EGAF00002034781 bam 37.7 MB
EGAF00002034782 bam 51.4 MB
EGAF00002034783 bam 24.1 MB
EGAF00002034784 bam 67.6 MB
EGAF00002034785 bam 73.9 MB
EGAF00002034786 bam 65.4 MB
EGAF00002034787 bam 64.6 MB
EGAF00002034788 bam 54.4 MB
EGAF00002034789 bam 65.5 MB
EGAF00002034790 bam 81.5 MB
EGAF00002034791 bam 82.1 MB
EGAF00002034792 bam 51.4 MB
EGAF00002034793 bam 46.2 MB
EGAF00002034794 bam 43.7 MB
EGAF00002034795 bam 49.9 MB
EGAF00002034796 bam 62.9 MB
EGAF00002034797 bam 66.4 MB
EGAF00002034798 bam 66.3 MB
EGAF00002034799 bam 76.7 MB
EGAF00002034800 bam 58.6 MB
EGAF00002034801 bam 69.3 MB
EGAF00002034802 bam 55.6 MB
EGAF00002034803 bam 88.7 MB
EGAF00002034804 bam 5.5 MB
EGAF00002034805 bam 17.2 MB
EGAF00002034806 bam 5.1 MB
EGAF00002034807 bam 5.9 MB
EGAF00002034808 bam 4.9 MB
EGAF00002034809 bam 4.5 MB
EGAF00002034810 bam 4.0 MB
EGAF00002034811 bam 4.5 MB
EGAF00002034812 bam 4.8 MB
EGAF00002034813 bam 6.4 MB
EGAF00002034814 bam 4.8 MB
EGAF00002034815 bam 4.9 MB
EGAF00002034816 bam 5.3 MB
EGAF00002034817 bam 5.0 MB
EGAF00002034818 bam 4.7 MB
EGAF00002034819 bam 5.5 MB
EGAF00002034820 bam 5.3 MB
EGAF00002034821 bam 5.6 MB
EGAF00002034822 bam 6.0 MB
EGAF00002034823 bam 3.7 MB
EGAF00002034824 bam 4.6 MB
EGAF00002034825 bam 4.9 MB
EGAF00002034826 bam 5.9 MB
EGAF00002034836 bam 68.2 MB
EGAF00002034837 bam 55.5 MB
EGAF00002034838 bam 24.3 MB
EGAF00002034839 bam 33.7 MB
EGAF00002034840 bam 43.5 MB
EGAF00002034841 bam 60.4 MB
EGAF00002034842 bam 61.1 MB
EGAF00002034843 bam 57.8 MB
EGAF00002034844 bam 70.5 MB
EGAF00002034845 bam 60.9 MB
EGAF00002034846 bam 64.7 MB
EGAF00002034847 bam 35.1 MB
EGAF00002034848 bam 37.5 MB
EGAF00002034849 bam 41.3 MB
EGAF00002034850 bam 73.2 MB
EGAF00002034851 bam 68.8 MB
EGAF00002034852 bam 70.0 MB
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EGAF00002034854 bam 79.9 MB
EGAF00002034855 bam 66.8 MB
EGAF00002034856 bam 102.0 MB
EGAF00002034857 bam 71.1 MB
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EGAF00002034878 bam 15.4 MB
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EGAF00002034901 bam 68.5 MB
EGAF00002034902 bam 54.2 MB
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EGAF00002034906 bam 62.8 MB
EGAF00002034907 bam 58.3 MB
EGAF00002034908 bam 74.3 MB
EGAF00002034909 bam 71.7 MB
EGAF00002034910 bam 15.0 MB
EGAF00002034911 bam 13.4 MB
EGAF00002034912 bam 18.2 MB
EGAF00002034913 bam 14.6 MB
EGAF00002034914 bam 12.4 MB
EGAF00002034915 bam 12.6 MB
EGAF00002034916 bam 16.6 MB
EGAF00002034917 bam 14.4 MB
EGAF00002034918 bam 12.0 MB
EGAF00002034919 bam 13.3 MB
EGAF00002034920 bam 13.8 MB
EGAF00002034955 bam 82.7 MB
EGAF00002034956 bam 83.6 MB
EGAF00002034957 bam 33.6 MB
EGAF00002034958 bam 77.5 MB
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EGAF00002034960 bam 63.2 MB
EGAF00002034961 bam 95.4 MB
EGAF00002034962 bam 65.7 MB
EGAF00002034963 bam 78.4 MB
EGAF00002034964 bam 64.4 MB
EGAF00002034965 bam 54.6 MB
EGAF00002034966 bam 64.1 MB
EGAF00002034967 bam 71.5 MB
EGAF00002034968 bam 82.3 MB
EGAF00002034969 bam 75.1 MB
EGAF00002034970 bam 81.0 MB
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EGAF00002035024 bam 68.7 MB
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EGAF00002035029 bam 72.0 MB
EGAF00002035030 bam 62.1 MB
EGAF00002035031 bam 63.7 MB
EGAF00002035032 bam 58.3 MB
EGAF00002035033 bam 76.8 MB
EGAF00002035034 bam 58.8 MB
EGAF00002035035 bam 28.8 MB
EGAF00002035036 bam 32.3 MB
EGAF00002035037 bam 32.2 MB
EGAF00002035038 bam 53.6 MB
EGAF00002035039 bam 57.9 MB
EGAF00002035040 bam 71.8 MB
EGAF00002035041 bam 64.0 MB
EGAF00002035042 bam 92.0 MB
EGAF00002035043 bam 52.6 MB
EGAF00002035044 bam 33.0 MB
EGAF00002035045 bam 55.8 MB
EGAF00002035092 bam 32.7 MB
EGAF00002035093 bam 53.0 MB
EGAF00002035094 bam 39.3 MB
EGAF00002035095 bam 46.9 MB
EGAF00002035096 bam 57.6 MB
EGAF00002035097 bam 73.0 MB
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600 Files (21.4 GB)