Dataset

Whole exome sequencing data of tumor/normal pairs for the study "TGF-β attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells"

Dataset ID Technology Samples
EGAD00001004218 Illumina HiSeq 2500 488

Dataset Description

Tumor DNA was extracted from formalin-fixed and paraffin embedded tumors of a large cohort of bladder cancer patients before treatment with anti-PD-L1. Normal DNA was extracted from matched PBMCs. Whole exome sequencing was performed. This is a subset of patients for which RNA sequencing is also provided (with more detailed phenotypic information).

Who controls access to this dataset

For each dataset that requires controlled access, there is a corresponding Data Access Committee (DAC) who determine access permissions. Access to actual data files is not managed by the EGA. If you need to request access to this data set, please contact:

Data access committee handling data access requests for biomarker data from the clinical trial IMvigor210.
Contact person: Sanjeev Mariathasan
Email: devsci-dac-d [at] gene [dot] com
More details: EGAC00001000945

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