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WES, ultra-deep sequencing exome and RNAseq data of diseased liver samples

1. Utra-deep exome sequencing data, illumina pair-end reads, fastq, 190 samples 2. WES data, illumina pair-end reads, fastq, 120 samples 3. RNA-seq data, illumina, pair-end reads, fastq, 20 samples

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DATA ACCESS AGREEMENT for cirrhosis data

DATA ACCESS AGREEMENT These terms and conditions govern access to the managed access datasets (details of which are set out in Appendix I) to which the User Institution has requested access. The User Institution agrees to be bound by these terms and conditions. Definitions Authorised Personnel: The individuals at the User Institution to whom Hao Zhu grants access to the Data. This includes the User, the individuals listed in Appendix II and any other individuals for whom the User Institution subsequently requests access to the Data. Details of the initial Authorised Personnel are set out in Appendix II. Data: The managed access datasets to which the User Institution has requested access. Data Producers: Hao Zhu and the collaborators listed in Appendix I responsible for the development, organization, and oversight of these Data. External Collaborator: A collaborator of the User, working for an institution other than the User Institution. Project: The project for which the User Institution has requested access to these Data. A description of the Project is set out in Appendix II. Publications: Includes, without limitation, articles published in print journals, electronic journals, reviews, books, posters and other written and verbal presentations of research. Research Participant: An individual whose data form part of these Data. Research Purposes: Shall mean research that is seeking to advance the understanding of genetics and genomics, including the treatment of disorders, and work on statistical methods that may be applied to such research. User: The principal investigator for the Project. User Institution(s): The Institution that has requested access to the Data. XXXXX: Your Institution details here 1. The User Institution agrees to only use these Data for the purpose of the Project (described in Appendix II) and only for Research Purposes. The User Institution further agrees that it will only use these Data for Research Purposes which are within the limitations (if any) set out in Appendix I. 2. The User Institution agrees to preserve, at all times, the confidentiality of these Data. In particular, it undertakes not to use, or attempt to use these Data to compromise or otherwise infringe the confidentiality of information on Research Participants. Without prejudice to the generality of the foregoing, the User Institution agrees to use at least the measures set out in Appendix I to protect these Data. 3. The User Institution agrees to protect the confidentiality of Research Participants in any research papers or publications that they prepare by taking all reasonable care to limit the possibility of identification. 4. The User Institution agrees not to link or combine these Data to other information or archived data available in a way that could re-identify the Research Participants, even if access to that data has been formally granted to the User Institution or is freely available without restriction. 5. The User Institution agrees only to transfer or disclose these Data, in whole or part, or any material derived from these Data, to the Authorised Personnel. Should the User Institution wish to share these Data with an External Collaborator, the External Collaborator must complete a separate application for access to these Data. 6. The User Institution agrees that the Data Producers, and all other parties involved in the creation, funding or protection of these Data: a) make no warranty or representation, express or implied as to the accuracy, quality or comprehensiveness of these Data; b) exclude to the fullest extent permitted by law all liability for actions, claims, proceedings, demands, losses (including but not limited to loss of profit), costs, awards damages and payments made by the Recipient that may arise (whether directly or indirectly) in any way whatsoever from the Recipient’s use of these Data or from the unavailability of, or break in access to, these Data for whatever reason and; c) bear no responsibility for the further analysis or interpretation of these Data. 7. The User Institution agrees to follow the Fort Lauderdale Guidelines (http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtd003207.pdf ) and the Toronto Statement (http://www.nature.com/nature/journal/v461/n7261/full/461168a.html). This includes but is not limited to recognising the contribution of the Data Producers and including a proper acknowledgement in all reports or publications resulting from the use of these Data. 8. The User Institution agrees to follow the Publication Policy in Appendix III. This includes respecting the moratorium period for the Data Producers to publish the first peer-reviewed report describing and analysing these Data. 9. The User Institution agrees not to make intellectual property claims on these Data and not to use intellectual property protection in ways that would prevent or block access to, or use of, any element of these Data, or conclusion drawn directly from these Data. 10. The User Institution can elect to perform further research that would add intellectual and resource capital to these data and decide to obtain intellectual property rights on these downstream discoveries. In this case, the User Institution agrees to implement licensing policies that will not obstruct further research and to follow the U.S. National Institutes of Health Best Practices for the Licensing of Genomic Inventions (2005) (https://www.icgc.org/files/daco/NIH_BestPracticesLicensingGenomicInventions_2005_en.pdf ) in conformity with the Organisation for Economic Co-operation and Development Guidelines for the Licensing of the Genetic Inventions (2006) (http://www.oecd.org/science/biotech/36198812.pdf ). 11. The User Institution agrees to destroy/discard the Data held, once it is no longer used for the Project, unless obliged to retain the data for archival purposes in conformity with audit or legal requirements. 12. The User Institution will notify DAC within 30 days of any changes or departures of Authorised Personnel. 13. The User Institution will notify DAC prior to any significant changes to the protocol for the Project. 14. The User Institution will notify DAC as soon as it becomes aware of a breach of the terms or conditions of this agreement. 15. DAC may terminate this agreement by written notice to the User Institution. If this agreement terminates for any reason, the User Institution will be required to destroy any Data held, including copies and backup copies. This clause does not prevent the User Institution from retaining these data for archival purpose in conformity with audit or legal requirements. 16. The User Institution accepts that it may be necessary for the Data Producers to alter the terms of this agreement from time to time. In the event that changes are required, the Data Producers or their appointed agent will contact the User Institution to inform it of the changes and the User Institution may elect to accept the changes or terminate the agreement. 17. If requested, the User Institution will allow data security and management documentation to be inspected to verify that it is complying with the terms of this agreement. 18. The User Institution agrees to distribute a copy of these terms to the Authorised Personnel. The User Institution will procure that the Authorised Personnel comply with the terms of this agreement. 19. This agreement (and any dispute, controversy, proceedings or claim of whatever nature arising out of this agreement or its formation) shall be construed, interpreted and governed by the laws of England and Wales and shall be subject to the exclusive jurisdiction of the English courts. Agreed for User Institution Signature: Name: Title: Date: Principal Investigator I confirm that I have read and understood this Agreement. Signature: Name: Title: Date: Agreed for Hao Zhu Signature: Name: Hao Zhu Title: Assistant Professor Date: APPENDIX I – DATASET DETAILS APPENDIX II ––PROJECT DETAILS APPENDIX III –– PUBLICATION POLICY APPENDIX I – DATASET DETAILS (to be completed by the data producer before passing to applicant) Dataset reference (EGA Study ID and Dataset Details) Name of project that created the dataset Somatic mutations increase hepatic clonal fitness and regeneration in chronic liver disease. Names of other data producers/collaborators Hao Zhu, Min Zhu, Tianshi Lu, Yuemeng Jia, Xin Luo, Purva Gopal, Lin Li, Mobolaji Odewole, Veronica Renteria, Amit G. Singal, Younghoon Jang, Kai Ge, Sam C. Wang, Justin R. Parekh, Malcolm P. MacConmara, Adam C. Yopp, Tao Wang Specific limitations on areas of research Academic research Minimum protection measures required The data should be accessed by only the persons listed in the agreement between User and DAC. The data should be stored on a computer system behind the network firewall and the network to which the computer system storing data is connected should not be exposed the public internet. File access: Data can be held in unencrypted files on an institutional compute system, with Unix user group read/write access for one or more appropriate groups but not Unix world read/write access behind a secure firewall. Laptops holding these data should have password protected logins and screenlocks (set to lock after 5 min of inactivity). If held on USB keys or other portable hard drives, the data must be encrypted. APPENDIX II – PROJECT DETAILS (to be completed by the Requestor) Details of dataset requested i.e., EGA Study and Dataset Accession Number Brief abstract of the Project in which the Data will be used (500 words max) Normal tissues accumulate genetic changes, but it is unknown if mutations promote clonal expansion of normal cells in response to chronic injury. Exome sequencing of diseased liver samples from 83 patients revealed a complex mutational landscape in cirrhosis. Additional ultra-deep sequencing identified recurrent mutations in PKD1, PPARGC1B, KMT2D, and ARID1A. The number and size of mutant clones increased as a function of fibrosis stage and tissue damage. Also, chromosome 1 and 8 gains were observed, suggesting aneuploidy. To interrogate the functional impact of mutated genes, a pooled in vivo CRISPR screening approach was established. In agreement with sequencing results, examination of 147 genes again revealed that loss of Pkd1, Kmt2d, and Arid1a promoted clonal expansion. Conditional heterozygous deletion of these genes was also hepatoprotective in injury assays. Pre-malignant somatic alterations are often viewed through the lens of cancer, but we show that mutations can promote regeneration, likely independent of carcinogenesis. All Individuals who the User Institution to be named as registered users Name of Registered User Email Job Title Supervisor* All Individuals that should have an account created at the EGA Name of Registered User Email Job Title APPENDIX III – PUBLICATION POLICY Hao Zhu and the collaborators listed in Appendix I intend to publish the results of their analysis of this dataset and do not consider its deposition into public databases to be the equivalent of such publications. Hao Zhu and the collaborators listed in Appendix I anticipate that the dataset could be useful to other qualified researchers for a variety of purposes. However, some areas of work are subject to a publication moratorium. The publication moratorium covers any publications (including oral communications) that describe the use of the dataset. For research papers, submission for publication should not occur until 12 months after these data were first made available on the relevant hosting database, unless DAC has provided written consent to earlier submission. In any publications based on these data, please describe how the data can be accessed, including the name of the hosting database (e.g., The European Genome-phenome Archive at the European Bioinformatics Institute) and its accession numbers (e.g., EGAS00000000029), and acknowledge its use in a form agreed by the User Institution with DAC.

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001003496 Other

This table displays only public information pertaining to the files in the dataset. If you wish to access this dataset, please submit a request. If you already have access to these data files, please consult the download documentation.

ID File Type Size Located in
EGAF00002395741 fastq.gz 3.3 GB
EGAF00002395742 fastq.gz 3.7 GB
EGAF00002395743 fastq.gz 3.4 GB
EGAF00002395744 fastq.gz 3.8 GB
EGAF00002395745 fastq.gz 5.2 GB
EGAF00002395746 fastq.gz 5.8 GB
EGAF00002395747 fastq.gz 4.1 GB
EGAF00002395748 fastq.gz 4.8 GB
EGAF00002395749 fastq.gz 5.2 GB
EGAF00002395750 fastq.gz 5.8 GB
EGAF00002395751 fastq.gz 5.4 GB
EGAF00002395752 fastq.gz 6.3 GB
EGAF00002395753 fastq.gz 3.0 GB
EGAF00002395754 fastq.gz 3.5 GB
EGAF00002395755 fastq.gz 4.0 GB
EGAF00002395756 fastq.gz 4.5 GB
EGAF00002395757 fastq.gz 4.1 GB
EGAF00002395758 fastq.gz 4.6 GB
EGAF00002395759 fastq.gz 3.8 GB
EGAF00002395760 fastq.gz 4.2 GB
EGAF00002395761 fastq.gz 3.3 GB
EGAF00002395762 fastq.gz 3.7 GB
EGAF00002395763 fastq.gz 3.9 GB
EGAF00002395764 fastq.gz 4.4 GB
EGAF00002395765 fastq.gz 4.9 GB
EGAF00002395766 fastq.gz 5.5 GB
EGAF00002395767 fastq.gz 3.5 GB
EGAF00002395768 fastq.gz 4.0 GB
EGAF00002395769 fastq.gz 4.0 GB
EGAF00002395770 fastq.gz 4.6 GB
EGAF00002395771 fastq.gz 4.4 GB
EGAF00002395772 fastq.gz 5.0 GB
EGAF00002395773 fastq.gz 3.1 GB
EGAF00002395774 fastq.gz 3.5 GB
EGAF00002395775 fastq.gz 8.4 GB
EGAF00002395776 fastq.gz 9.6 GB
EGAF00002395777 fastq.gz 3.9 GB
EGAF00002395778 fastq.gz 4.4 GB
EGAF00002395779 fastq.gz 3.3 GB
EGAF00002395780 fastq.gz 3.7 GB
EGAF00002395781 fastq.gz 4.3 GB
EGAF00002395782 fastq.gz 4.8 GB
EGAF00002395783 fastq.gz 2.7 GB
EGAF00002395784 fastq.gz 3.0 GB
EGAF00002395785 fastq.gz 2.2 GB
EGAF00002395786 fastq.gz 2.3 GB
EGAF00002395787 fastq.gz 2.5 GB
EGAF00002395788 fastq.gz 2.7 GB
EGAF00002395789 fastq.gz 2.7 GB
EGAF00002395790 fastq.gz 3.0 GB
EGAF00002395791 fastq.gz 3.0 GB
EGAF00002395792 fastq.gz 3.3 GB
EGAF00002395793 fastq.gz 2.8 GB
EGAF00002395794 fastq.gz 3.0 GB
EGAF00002395795 fastq.gz 2.3 GB
EGAF00002395796 fastq.gz 2.5 GB
EGAF00002395797 fastq.gz 2.8 GB
EGAF00002395798 fastq.gz 3.1 GB
EGAF00002395799 fastq.gz 2.7 GB
EGAF00002395800 fastq.gz 2.9 GB
EGAF00002395801 fastq.gz 2.8 GB
EGAF00002395802 fastq.gz 3.1 GB
EGAF00002395803 fastq.gz 2.5 GB
EGAF00002395804 fastq.gz 2.7 GB
EGAF00002395805 fastq.gz 2.3 GB
EGAF00002395806 fastq.gz 2.5 GB
EGAF00002395807 fastq.gz 2.6 GB
EGAF00002395808 fastq.gz 2.8 GB
EGAF00002395809 fastq.gz 2.6 GB
EGAF00002395810 fastq.gz 2.8 GB
EGAF00002395811 fastq.gz 3.2 GB
EGAF00002395812 fastq.gz 3.5 GB
EGAF00002395813 fastq.gz 2.4 GB
EGAF00002395814 fastq.gz 2.6 GB
EGAF00002395815 fastq.gz 2.1 GB
EGAF00002395816 fastq.gz 2.3 GB
EGAF00002395817 fastq.gz 2.7 GB
EGAF00002395818 fastq.gz 2.9 GB
EGAF00002395819 fastq.gz 2.4 GB
EGAF00002395820 fastq.gz 2.6 GB
EGAF00002395821 fastq.gz 2.4 GB
EGAF00002395822 fastq.gz 2.6 GB
EGAF00002395823 fastq.gz 3.3 GB
EGAF00002395824 fastq.gz 3.7 GB
EGAF00002395825 fastq.gz 2.8 GB
EGAF00002395826 fastq.gz 3.0 GB
EGAF00002395827 fastq.gz 3.1 GB
EGAF00002395828 fastq.gz 3.4 GB
EGAF00002395829 fastq.gz 2.9 GB
EGAF00002395830 fastq.gz 3.2 GB
EGAF00002395831 fastq.gz 3.1 GB
EGAF00002395832 fastq.gz 3.5 GB
EGAF00002395833 fastq.gz 2.9 GB
EGAF00002395834 fastq.gz 3.1 GB
EGAF00002395835 fastq.gz 2.9 GB
EGAF00002395836 fastq.gz 3.1 GB
EGAF00002395837 fastq.gz 2.2 GB
EGAF00002395838 fastq.gz 2.4 GB
EGAF00002395839 fastq.gz 2.6 GB
EGAF00002395840 fastq.gz 2.9 GB
EGAF00002395841 fastq.gz 2.6 GB
EGAF00002395842 fastq.gz 2.8 GB
EGAF00002395843 fastq.gz 2.3 GB
EGAF00002395844 fastq.gz 2.5 GB
EGAF00002395845 fastq.gz 2.1 GB
EGAF00002395846 fastq.gz 2.2 GB
EGAF00002395847 fastq.gz 2.2 GB
EGAF00002395848 fastq.gz 2.4 GB
EGAF00002395849 fastq.gz 2.2 GB
EGAF00002395850 fastq.gz 2.4 GB
EGAF00002395851 fastq.gz 2.4 GB
EGAF00002395852 fastq.gz 2.6 GB
EGAF00002395853 fastq.gz 5.1 GB
EGAF00002395854 fastq.gz 5.6 GB
EGAF00002395855 fastq.gz 4.7 GB
EGAF00002395856 fastq.gz 5.1 GB
EGAF00002395857 fastq.gz 2.1 GB
EGAF00002395858 fastq.gz 2.3 GB
EGAF00002395859 fastq.gz 3.0 GB
EGAF00002395860 fastq.gz 3.3 GB
EGAF00002395861 fastq.gz 2.6 GB
EGAF00002395862 fastq.gz 2.8 GB
EGAF00002395863 fastq.gz 2.1 GB
EGAF00002395864 fastq.gz 2.3 GB
EGAF00002395865 fastq.gz 2.3 GB
EGAF00002395866 fastq.gz 2.5 GB
EGAF00002395867 fastq.gz 2.6 GB
EGAF00002395868 fastq.gz 2.8 GB
EGAF00002395869 fastq.gz 1.7 GB
EGAF00002395870 fastq.gz 1.8 GB
EGAF00002395871 fastq.gz 2.5 GB
EGAF00002395872 fastq.gz 2.7 GB
EGAF00002395873 fastq.gz 2.5 GB
EGAF00002395874 fastq.gz 2.7 GB
EGAF00002395875 fastq.gz 2.3 GB
EGAF00002395876 fastq.gz 2.5 GB
EGAF00002395877 fastq.gz 2.4 GB
EGAF00002395878 fastq.gz 2.6 GB
EGAF00002395879 fastq.gz 2.3 GB
EGAF00002395880 fastq.gz 2.5 GB
EGAF00002395881 fastq.gz 2.6 GB
EGAF00002395882 fastq.gz 2.8 GB
EGAF00002395883 fastq.gz 3.1 GB
EGAF00002395884 fastq.gz 3.3 GB
EGAF00002395885 fastq.gz 3.1 GB
EGAF00002395886 fastq.gz 3.3 GB
EGAF00002395887 fastq.gz 2.5 GB
EGAF00002395888 fastq.gz 2.8 GB
EGAF00002395889 fastq.gz 3.0 GB
EGAF00002395890 fastq.gz 3.3 GB
EGAF00002395891 fastq.gz 2.2 GB
EGAF00002395892 fastq.gz 2.3 GB
EGAF00002395893 fastq.gz 2.2 GB
EGAF00002395894 fastq.gz 2.4 GB
EGAF00002395895 fastq.gz 2.0 GB
EGAF00002395896 fastq.gz 2.2 GB
EGAF00002395897 fastq.gz 2.1 GB
EGAF00002395898 fastq.gz 2.3 GB
EGAF00002395899 fastq.gz 2.9 GB
EGAF00002395900 fastq.gz 3.2 GB
EGAF00002395901 fastq.gz 2.4 GB
EGAF00002395902 fastq.gz 2.6 GB
EGAF00002395903 fastq.gz 2.8 GB
EGAF00002395904 fastq.gz 3.1 GB
EGAF00002395905 fastq.gz 2.9 GB
EGAF00002395906 fastq.gz 3.2 GB
EGAF00002395907 fastq.gz 2.3 GB
EGAF00002395908 fastq.gz 2.5 GB
EGAF00002395909 fastq.gz 2.2 GB
EGAF00002395910 fastq.gz 2.4 GB
EGAF00002395911 fastq.gz 2.1 GB
EGAF00002395912 fastq.gz 2.3 GB
EGAF00002395913 fastq.gz 2.0 GB
EGAF00002395914 fastq.gz 2.2 GB
EGAF00002395915 fastq.gz 2.4 GB
EGAF00002395916 fastq.gz 2.6 GB
EGAF00002395917 fastq.gz 2.3 GB
EGAF00002395918 fastq.gz 2.5 GB
EGAF00002395919 fastq.gz 2.2 GB
EGAF00002395920 fastq.gz 2.4 GB
EGAF00002395921 fastq.gz 2.3 GB
EGAF00002395922 fastq.gz 2.5 GB
EGAF00002395923 fastq.gz 2.2 GB
EGAF00002395924 fastq.gz 2.4 GB
EGAF00002395925 fastq.gz 2.0 GB
EGAF00002395926 fastq.gz 2.1 GB
EGAF00002395927 fastq.gz 2.7 GB
EGAF00002395928 fastq.gz 3.0 GB
EGAF00002395929 fastq.gz 2.6 GB
EGAF00002395930 fastq.gz 2.8 GB
EGAF00002395931 fastq.gz 2.3 GB
EGAF00002395932 fastq.gz 2.5 GB
EGAF00002395933 fastq.gz 2.5 GB
EGAF00002395934 fastq.gz 2.8 GB
EGAF00002395935 fastq.gz 2.3 GB
EGAF00002395936 fastq.gz 2.6 GB
EGAF00002395937 fastq.gz 2.5 GB
EGAF00002395938 fastq.gz 2.7 GB
EGAF00002395939 fastq.gz 2.8 GB
EGAF00002395940 fastq.gz 3.0 GB
EGAF00002395941 fastq.gz 1.7 GB
EGAF00002395942 fastq.gz 1.8 GB
EGAF00002395943 fastq.gz 2.1 GB
EGAF00002395944 fastq.gz 2.3 GB
EGAF00002395945 fastq.gz 2.4 GB
EGAF00002395946 fastq.gz 2.6 GB
EGAF00002395947 fastq.gz 2.5 GB
EGAF00002395948 fastq.gz 2.7 GB
EGAF00002395949 fastq.gz 2.7 GB
EGAF00002395950 fastq.gz 2.9 GB
EGAF00002395951 fastq.gz 3.2 GB
EGAF00002395952 fastq.gz 3.5 GB
EGAF00002395953 fastq.gz 2.8 GB
EGAF00002395954 fastq.gz 3.0 GB
EGAF00002395955 fastq.gz 2.4 GB
EGAF00002395956 fastq.gz 2.6 GB
EGAF00002395957 fastq.gz 2.7 GB
EGAF00002395958 fastq.gz 3.0 GB
EGAF00002395959 fastq.gz 2.5 GB
EGAF00002395960 fastq.gz 2.7 GB
EGAF00002395961 fastq.gz 2.4 GB
EGAF00002395962 fastq.gz 2.6 GB
EGAF00002395963 fastq.gz 2.5 GB
EGAF00002395964 fastq.gz 2.7 GB
EGAF00002395965 fastq.gz 2.2 GB
EGAF00002395966 fastq.gz 2.3 GB
EGAF00002395967 fastq.gz 2.6 GB
EGAF00002395968 fastq.gz 2.7 GB
EGAF00002395969 fastq.gz 2.2 GB
EGAF00002395970 fastq.gz 2.4 GB
EGAF00002395971 fastq.gz 2.3 GB
EGAF00002395972 fastq.gz 2.5 GB
EGAF00002395973 fastq.gz 2.6 GB
EGAF00002395974 fastq.gz 2.9 GB
EGAF00002395975 fastq.gz 2.4 GB
EGAF00002395976 fastq.gz 2.7 GB
EGAF00002395977 fastq.gz 2.5 GB
EGAF00002395978 fastq.gz 2.8 GB
EGAF00002395979 fastq.gz 2.6 GB
EGAF00002395980 fastq.gz 2.8 GB
EGAF00002395981 fastq.gz 2.2 GB
EGAF00002395982 fastq.gz 2.5 GB
EGAF00002395983 fastq.gz 2.9 GB
EGAF00002395984 fastq.gz 3.2 GB
EGAF00002395985 fastq.gz 2.6 GB
EGAF00002395986 fastq.gz 2.9 GB
EGAF00002395987 fastq.gz 2.7 GB
EGAF00002395988 fastq.gz 2.9 GB
EGAF00002395989 fastq.gz 2.5 GB
EGAF00002395990 fastq.gz 2.8 GB
EGAF00002395991 fastq.gz 2.6 GB
EGAF00002395992 fastq.gz 2.8 GB
EGAF00002395993 fastq.gz 2.7 GB
EGAF00002395994 fastq.gz 2.9 GB
EGAF00002395995 fastq.gz 2.5 GB
EGAF00002395996 fastq.gz 2.8 GB
EGAF00002395997 fastq.gz 2.4 GB
EGAF00002395998 fastq.gz 2.6 GB
EGAF00002395999 fastq.gz 2.7 GB
EGAF00002396000 fastq.gz 3.0 GB
EGAF00002396001 fastq.gz 2.8 GB
EGAF00002396002 fastq.gz 3.1 GB
EGAF00002396003 fastq.gz 2.4 GB
EGAF00002396004 fastq.gz 2.6 GB
EGAF00002396005 fastq.gz 2.4 GB
EGAF00002396006 fastq.gz 2.7 GB
EGAF00002396007 fastq.gz 2.0 GB
EGAF00002396008 fastq.gz 2.3 GB
EGAF00002396009 fastq.gz 2.9 GB
EGAF00002396010 fastq.gz 3.2 GB
EGAF00002396011 fastq.gz 2.4 GB
EGAF00002396012 fastq.gz 2.7 GB
EGAF00002396013 fastq.gz 2.5 GB
EGAF00002396014 fastq.gz 2.8 GB
EGAF00002396015 fastq.gz 3.1 GB
EGAF00002396016 fastq.gz 3.5 GB
EGAF00002396017 fastq.gz 2.8 GB
EGAF00002396018 fastq.gz 3.1 GB
EGAF00002396019 fastq.gz 2.5 GB
EGAF00002396020 fastq.gz 2.7 GB
EGAF00002396021 fastq.gz 2.5 GB
EGAF00002396022 fastq.gz 2.7 GB
EGAF00002396023 fastq.gz 2.4 GB
EGAF00002396024 fastq.gz 2.7 GB
EGAF00002396025 fastq.gz 3.2 GB
EGAF00002396026 fastq.gz 3.5 GB
EGAF00002396027 fastq.gz 3.2 GB
EGAF00002396028 fastq.gz 3.5 GB
EGAF00002396029 fastq.gz 2.4 GB
EGAF00002396030 fastq.gz 2.6 GB
EGAF00002396031 fastq.gz 2.3 GB
EGAF00002396032 fastq.gz 2.6 GB
EGAF00002396033 fastq.gz 3.8 GB
EGAF00002396034 fastq.gz 4.1 GB
EGAF00002396035 fastq.gz 2.8 GB
EGAF00002396036 fastq.gz 3.0 GB
EGAF00002396037 fastq.gz 2.5 GB
EGAF00002396038 fastq.gz 2.7 GB
EGAF00002396039 fastq.gz 2.6 GB
EGAF00002396040 fastq.gz 2.8 GB
EGAF00002396041 fastq.gz 2.6 GB
EGAF00002396042 fastq.gz 2.9 GB
EGAF00002396043 fastq.gz 3.2 GB
EGAF00002396044 fastq.gz 3.5 GB
EGAF00002396045 fastq.gz 2.7 GB
EGAF00002396046 fastq.gz 3.0 GB
EGAF00002396047 fastq.gz 2.4 GB
EGAF00002396048 fastq.gz 2.6 GB
EGAF00002396049 fastq.gz 2.2 GB
EGAF00002396050 fastq.gz 2.4 GB
EGAF00002396051 fastq.gz 2.5 GB
EGAF00002396052 fastq.gz 2.8 GB
EGAF00002396053 fastq.gz 2.8 GB
EGAF00002396054 fastq.gz 3.1 GB
EGAF00002396055 fastq.gz 2.7 GB
EGAF00002396056 fastq.gz 3.0 GB
EGAF00002396057 fastq.gz 2.7 GB
EGAF00002396058 fastq.gz 3.0 GB
EGAF00002396059 fastq.gz 2.9 GB
EGAF00002396060 fastq.gz 3.2 GB
EGAF00002396061 fastq.gz 2.7 GB
EGAF00002396062 fastq.gz 3.0 GB
EGAF00002396063 fastq.gz 2.3 GB
EGAF00002396064 fastq.gz 2.6 GB
EGAF00002396065 fastq.gz 2.0 GB
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EGAF00002396202 fastq.gz 7.4 GB
EGAF00002396203 fastq.gz 15.3 GB
EGAF00002396204 fastq.gz 17.4 GB
EGAF00002396205 fastq.gz 2.3 GB
EGAF00002396206 fastq.gz 2.5 GB
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EGAF00002396208 fastq.gz 5.9 GB
EGAF00002396209 fastq.gz 2.8 GB
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EGAF00002396211 fastq.gz 3.9 GB
EGAF00002396212 fastq.gz 4.4 GB
EGAF00002396213 fastq.gz 3.1 GB
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EGAF00002396216 fastq.gz 5.0 GB
EGAF00002396217 fastq.gz 2.7 GB
EGAF00002396218 fastq.gz 3.0 GB
EGAF00002396219 fastq.gz 3.6 GB
EGAF00002396220 fastq.gz 4.1 GB
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EGAF00002396222 fastq.gz 2.4 GB
EGAF00002396223 fastq.gz 4.2 GB
EGAF00002396224 fastq.gz 4.8 GB
EGAF00002396225 fastq.gz 2.1 GB
EGAF00002396226 fastq.gz 2.3 GB
EGAF00002396227 fastq.gz 4.2 GB
EGAF00002396228 fastq.gz 4.8 GB
EGAF00002396229 fastq.gz 2.6 GB
EGAF00002396230 fastq.gz 2.8 GB
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EGAF00002396232 fastq.gz 4.7 GB
EGAF00002396233 fastq.gz 2.4 GB
EGAF00002396234 fastq.gz 2.7 GB
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EGAF00002396247 fastq.gz 5.0 GB
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EGAF00002396251 fastq.gz 4.6 GB
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EGAF00002396271 fastq.gz 7.6 GB
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EGAF00002396278 fastq.gz 6.8 GB
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EGAF00002396282 fastq.gz 4.6 GB
EGAF00002396283 fastq.gz 2.3 GB
EGAF00002396284 fastq.gz 2.6 GB
EGAF00002396285 fastq.gz 5.5 GB
EGAF00002396286 fastq.gz 6.3 GB
EGAF00002396287 fastq.gz 3.8 GB
EGAF00002396288 fastq.gz 4.4 GB
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EGAF00002396290 fastq.gz 5.8 GB
EGAF00002396291 fastq.gz 3.8 GB
EGAF00002396292 fastq.gz 4.4 GB
EGAF00002396293 fastq.gz 3.4 GB
EGAF00002396294 fastq.gz 3.9 GB
EGAF00002396295 fastq.gz 5.7 GB
EGAF00002396296 fastq.gz 6.5 GB
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EGAF00002396301 fastq.gz 3.9 GB
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EGAF00002396304 fastq.gz 4.6 GB
EGAF00002396305 fastq.gz 4.2 GB
EGAF00002396306 fastq.gz 4.8 GB
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EGAF00002396308 fastq.gz 4.1 GB
EGAF00002396309 fastq.gz 3.9 GB
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EGAF00002396311 fastq.gz 13.1 GB
EGAF00002396312 fastq.gz 15.2 GB
EGAF00002396313 fastq.gz 3.8 GB
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EGAF00002396315 fastq.gz 4.8 GB
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EGAF00002396317 fastq.gz 4.6 GB
EGAF00002396318 fastq.gz 5.2 GB
EGAF00002396319 fastq.gz 4.9 GB
EGAF00002396320 fastq.gz 5.7 GB
EGAF00002396321 fastq.gz 9.1 GB
EGAF00002396322 fastq.gz 10.3 GB
EGAF00002396323 fastq.gz 4.9 GB
EGAF00002396324 fastq.gz 5.5 GB
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EGAF00002396337 fastq.gz 4.0 GB
EGAF00002396338 fastq.gz 4.4 GB
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EGAF00002396341 fastq.gz 4.8 GB
EGAF00002396342 fastq.gz 5.3 GB
EGAF00002396343 fastq.gz 3.3 GB
EGAF00002396344 fastq.gz 3.6 GB
EGAF00002396345 fastq.gz 5.2 GB
EGAF00002396346 fastq.gz 5.8 GB
EGAF00002396347 fastq.gz 4.6 GB
EGAF00002396348 fastq.gz 5.1 GB
EGAF00002396349 fastq.gz 3.6 GB
EGAF00002396350 fastq.gz 4.1 GB
EGAF00002396351 fastq.gz 4.4 GB
EGAF00002396352 fastq.gz 5.1 GB
EGAF00002396353 fastq.gz 4.9 GB
EGAF00002396354 fastq.gz 5.5 GB
EGAF00002396355 fastq.gz 4.9 GB
EGAF00002396356 fastq.gz 5.4 GB
EGAF00002396357 fastq.gz 3.6 GB
EGAF00002396358 fastq.gz 4.1 GB
EGAF00002396359 fastq.gz 2.6 GB
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EGAF00002396362 fastq.gz 3.2 GB
EGAF00002396363 fastq.gz 6.1 GB
EGAF00002396364 fastq.gz 7.0 GB
EGAF00002396365 fastq.gz 4.7 GB
EGAF00002396366 fastq.gz 5.2 GB
EGAF00002396367 fastq.gz 4.7 GB
EGAF00002396368 fastq.gz 5.5 GB
EGAF00002396369 fastq.gz 4.8 GB
EGAF00002396370 fastq.gz 5.5 GB
EGAF00002396371 fastq.gz 5.0 GB
EGAF00002396372 fastq.gz 5.5 GB
EGAF00002396373 fastq.gz 4.3 GB
EGAF00002396374 fastq.gz 4.8 GB
EGAF00002396375 fastq.gz 4.7 GB
EGAF00002396376 fastq.gz 5.2 GB
EGAF00002396377 fastq.gz 8.9 GB
EGAF00002396378 fastq.gz 9.2 GB
EGAF00002396379 fastq.gz 3.3 GB
EGAF00002396380 fastq.gz 3.7 GB
EGAF00002396381 fastq.gz 3.6 GB
EGAF00002396382 fastq.gz 4.1 GB
EGAF00002396383 fastq.gz 4.7 GB
EGAF00002396384 fastq.gz 5.3 GB
EGAF00002396385 fastq.gz 5.4 GB
EGAF00002396386 fastq.gz 6.2 GB
EGAF00002396387 fastq.gz 3.9 GB
EGAF00002396388 fastq.gz 4.4 GB
EGAF00002396389 fastq.gz 4.6 GB
EGAF00002396390 fastq.gz 5.0 GB
EGAF00002396391 fastq.gz 6.5 GB
EGAF00002396392 fastq.gz 7.5 GB
EGAF00002396393 fastq.gz 6.6 GB
EGAF00002396394 fastq.gz 7.3 GB
EGAF00002396395 fastq.gz 4.9 GB
EGAF00002396396 fastq.gz 5.6 GB
EGAF00002396397 fastq.gz 4.3 GB
EGAF00002396398 fastq.gz 4.8 GB
EGAF00002396399 fastq.gz 2.6 GB
EGAF00002396400 fastq.gz 3.0 GB
660 Files (2.4 TB)