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Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases. Cancer Discovery doi: 10.1158/2159-8290. PMID: 30787016 PMCID: PMC6497554

The BAM files for WES and RNA seq used in the article "Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases." on cancer Discovery 2019. PMID: 30787016 PMCID: PMC6497554. Authors : Grant M Fischer, ..., Michael A Davies.

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This is the data access policy which aims to ensure the data applicant agrees to the terms before the access approval.

DATA ACCESS AGREEMENT This Data Access Agreement (“Agreement”), effective as of the ____ day of _________________, 20__ (“Effective Date”), is by and between The University of Texas M. D. Anderson Cancer Center, an institution of The University of Texas System and an agency of the State of Texas, with an address at 1515 Holcombe Boulevard, Houston, Texas 77030 (“Provider”), and _____________ (“Recipient”) on behalf of its investigator _____________ (“Recipient Investigator”) (collectively, the “Parties”; each, a “Party”). RECITALS Provider maintains the following de-identified data in the European Genome-phenome Archive (EGA) managed by the European Bioinformatics Institute __[description of data]__ (“Data”), and Provider is willing to allow Recipient to access such Data from the EGA for the internal noncommercial research purposes of ___[research purpose]___ (“Purpose”), pursuant to the terms of this Agreement. In consideration of the mutual promises and covenants herein, and for other good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the Parties agree as follows: 1. The Data will be used solely for the Research by Recipient Investigator and personnel under his immediate supervision at Recipient, and may not be transferred to any other investigator or to any third party without prior written permission from Provider. The Material may not be used for any purpose other than the Research, including without limitation for any commercial purpose or for research in human subjects (including, without limitation, in diagnostic testing). 2. Neither Recipient nor Recipient Investigator shall disclose Data to any person or party other than the Recipient Investigator hereunder without Provider’s prior written consent. 3. The Data will be used in compliance with all applicable laws, regulations, and guidelines applicable to the Data, including without limitation any applicable export controls. 4. In any publication resulting from use of the Data, Recipient and Recipient Investigator shall acknowledge ______________ (“Provider Investigator”) and Provider as the provider of the Data. 5. This Agreement shall be effective as of the Effective Date and shall remain effective until completion of the Research. Either Party may terminate this Agreement with or without cause upon thirty (30) days’ written notice to the other Party. Upon expiration or termination of this Agreement for any reason, Recipient shall destroy all Data received pursuant to this Agreement. 6. Any notice permitted or required as provided for herein shall be in writing and to the contact and address as noted below or as may be provided by either party to the other in writing from time to time. Notice to Provider shall be to: Chief Legal Officer The University of Texas M. D. Anderson Cancer Center 1515 Holcombe Blvd., Unit 1674 Houston, Texas 77030 Phone: 713-745-6633; Facsimile: 713-745-6029 With a copy to: The University of Texas M. D. Anderson Cancer Center 1515 Holcombe Blvd., Unit 1676 Office of Research Administration Attn: AVP, Research Administration Houston, TX 77030 Phone: 713-792-3672; Facsimile: 713-792-7455 Notice to Recipient shall be to: __________________________ __________________________ __________________________ __________________________ __________________________ 7. In the event Protected Health Information (“PHI”), as defined by the federal Health Insurance Portability and Accountability Act of 1996 (“HIPAA”), as amended, is inadvertently created, accessed by, and/or disclosed to Recipient in connection with this Agreement, Recipient will immediately notify the Provider and will return to Provider or destroy such PHI, in accordance with the Provider’s instructions. Pending return or destruction of any PHI, Recipient shall maintain the confidentiality of all Data (including the PHI) and use appropriate safeguards to prevent access to, use, or disclosure of Data (including the PHI). 8. PROVIDER MAKES NO REPRESENTATION OR WARRANTY CONCERNING THE MATERIAL, INCLUDING WITHOUT LIMITATION, WARRANTY OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE OR ANY OTHER WARRANTY, EXPRESS OR IMPLIED. 9. Recipient Investigator and Recipient accept all liability for any use of the Data and for any loss, claim, or damage which may arise from or in connection with this Agreement or the use, handling or storage of the Data and in no event shall Provider or Provider Investigator be liable for any such use, loss, claim or damage. 10. This Agreement is via EGA mechanism. [Insert Recipient Name Here] THE UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER By: By: Name: ____________ ______ Name: ____________ Title: _____________ ______ Title: ____________ ______ Date: Date: Read and Understood: Read and Understood: Recipient Scientist: Provider Scientist: Name: ____________ ______ Name: ____________ Title: _____________ ______ Title: ____________ ______ Date: Date:

Studies are experimental investigations of a particular phenomenon, e.g., case-control studies on a particular trait or cancer research projects reporting matching cancer normal genomes from patients.

Study ID Study Title Study Type
EGAS00001003672 Other
ID File Type Size Located in
EGAF00002466353 bam 24.0 GB
EGAF00002466354 bam 27.1 GB
EGAF00002466355 bam 28.5 GB
EGAF00002466356 bam 20.6 GB
EGAF00002466357 bam 25.8 GB
EGAF00002466358 bam 21.5 GB
EGAF00002466359 bam 27.8 GB
EGAF00002466360 bam 25.7 GB
EGAF00002466361 bam 26.1 GB
EGAF00002466362 bam 19.6 GB
EGAF00002466363 bam 27.3 GB
EGAF00002466364 bam 26.4 GB
EGAF00002466365 bam 28.6 GB
EGAF00002466366 bam 24.7 GB
EGAF00002466367 bam 27.4 GB
EGAF00002466368 bam 24.4 GB
EGAF00002466369 bam 29.9 GB
EGAF00002466370 bam 24.0 GB
EGAF00002466371 bam 23.7 GB
EGAF00002466372 bam 18.0 GB
EGAF00002466373 bam 21.5 GB
EGAF00002466374 bam 20.4 GB
EGAF00002466375 bam 22.6 GB
EGAF00002466376 bam 17.8 GB
EGAF00002466377 bam 22.1 GB
EGAF00002466378 bam 19.7 GB
EGAF00002466379 bam 17.9 GB
EGAF00002466380 bam 14.9 GB
EGAF00002466381 bam 15.7 GB
EGAF00002466382 bam 22.9 GB
EGAF00002466383 bam 31.3 GB
EGAF00002466384 bam 24.8 GB
EGAF00002466385 bam 23.7 GB
EGAF00002466386 bam 30.0 GB
EGAF00002466387 bam 26.1 GB
EGAF00002466388 bam 28.7 GB
EGAF00002466389 bam 22.6 GB
EGAF00002466390 bam 15.7 GB
EGAF00002466391 bam 24.3 GB
EGAF00002466392 bam 29.6 GB
EGAF00002466393 bam 17.4 GB
EGAF00002466394 bam 18.9 GB
EGAF00002466395 bam 25.8 GB
EGAF00002466396 bam 26.4 GB
EGAF00002466397 bam 18.0 GB
EGAF00002466398 bam 13.4 GB
EGAF00002466399 bam 13.9 GB
EGAF00002466400 bam 14.7 GB
EGAF00002466401 bam 13.1 GB
EGAF00002466402 bam 19.3 GB
EGAF00002466403 bam 10.4 GB
EGAF00002466404 bam 13.3 GB
EGAF00002466405 bam 17.6 GB
EGAF00002466406 bam 11.9 GB
EGAF00002466407 bam 13.3 GB
EGAF00002466408 bam 10.5 GB
EGAF00002466409 bam 10.7 GB
EGAF00002466410 bam 17.5 GB
EGAF00002466411 bam 14.0 GB
EGAF00002466412 bam 16.4 GB
EGAF00002466413 bam 16.5 GB
EGAF00002466414 bam 4.7 GB
EGAF00002466415 bam 3.9 GB
EGAF00002466416 bam 3.5 GB
EGAF00002466417 bam 3.7 GB
EGAF00002466418 bam 3.2 GB
EGAF00002466419 bam 3.2 GB
EGAF00002466420 bam 3.1 GB
EGAF00002466421 bam 2.0 GB
EGAF00002466422 bam 1.6 GB
EGAF00002466423 bam 629.0 MB
EGAF00002466424 bam 719.3 MB
EGAF00002466425 bam 352.2 MB
EGAF00002466426 bam 4.2 GB
EGAF00002466427 bam 3.2 GB
EGAF00002466428 bam 1.7 GB
EGAF00002466429 bam 4.2 GB
EGAF00002466430 bam 3.7 GB
EGAF00002466431 bam 3.2 GB
EGAF00002466432 bam 3.1 GB
EGAF00002466433 bam 6.5 GB
EGAF00002466434 bam 3.0 GB
EGAF00002466435 bam 4.1 GB
EGAF00002466436 bam 1.3 GB
EGAF00002466437 bam 3.8 GB
EGAF00002466438 bam 3.3 GB
EGAF00002466439 bam 2.1 GB
EGAF00002466440 bam 4.3 GB
EGAF00002466441 bam 4.2 GB
EGAF00002466442 bam 4.1 GB
EGAF00002466443 bam 3.1 GB
EGAF00002466444 bam 3.5 GB
EGAF00002466445 bam 3.9 GB
EGAF00002466446 bam 2.3 GB
EGAF00002466447 bam 3.3 GB
EGAF00002466448 bam 2.6 GB
EGAF00002466449 bam 2.2 GB
EGAF00002466450 bam 3.7 GB
EGAF00002466451 bam 1.9 GB
EGAF00002466452 bam 4.2 GB
EGAF00002466453 bam 2.5 GB
EGAF00002466454 bam 2.1 GB
EGAF00002466455 bam 2.2 GB
EGAF00002466456 bam 2.4 GB
EGAF00002466457 bam 2.4 GB
EGAF00002466458 bam 3.5 GB
EGAF00002466459 bam 3.8 GB
EGAF00002466460 bam 3.3 GB
EGAF00002466461 bam 3.1 GB
EGAF00002466462 bam 4.5 GB
EGAF00002466463 bam 3.4 GB
EGAF00002466464 bam 2.7 GB
EGAF00002466465 bam 6.1 GB
EGAF00002466466 bam 4.8 GB
EGAF00002466467 bam 3.6 GB
EGAF00002466468 bam 5.0 GB
EGAF00002466469 bam 3.3 GB
EGAF00002466470 bam 2.8 GB
EGAF00002466471 bam 5.5 GB
EGAF00002466472 bam 2.0 GB
EGAF00002466473 bam 891.3 MB
EGAF00002466474 bam 2.7 GB
EGAF00002466475 bam 1.2 GB
EGAF00002466476 bam 1.8 GB
EGAF00002466477 bam 1.8 GB
EGAF00002466478 bam 1.9 GB
EGAF00002466479 bam 2.9 GB
EGAF00002466480 bam 3.7 GB
EGAF00002466481 bam 3.1 GB
EGAF00002466482 bam 1.7 GB
EGAF00002466483 bam 1.3 GB
EGAF00002466484 bam 997.3 MB
EGAF00002466485 bam 4.1 GB
EGAF00002466486 bam 4.4 GB
EGAF00002466487 bam 2.8 GB
EGAF00002466488 bam 2.8 GB
EGAF00002466489 bam 2.5 GB
EGAF00002466490 bam 4.2 GB
EGAF00002466491 bam 2.7 GB
EGAF00002466492 bam 712.7 MB
EGAF00002466493 bam 3.3 GB
EGAF00002466494 bam 2.8 GB
EGAF00002466495 bam 3.2 GB
EGAF00002466496 bam 3.0 GB
EGAF00002466497 bam 3.5 GB
EGAF00002466498 bam 8.1 GB
EGAF00002466499 bam 2.8 GB
EGAF00002466500 bam 4.8 GB
EGAF00002466501 bam 3.0 GB
EGAF00002466502 bam 3.5 GB
EGAF00002466503 bam 3.4 GB
EGAF00002466504 bam 4.7 GB
EGAF00002466505 bam 2.4 GB
EGAF00002466506 bam 3.7 GB
EGAF00002466507 bam 4.3 GB
EGAF00002466508 bam 5.7 GB
EGAF00002466509 bam 5.5 GB
EGAF00002466510 bam 6.0 GB
EGAF00002466511 bam 5.7 GB
EGAF00002466512 bam 3.0 GB
EGAF00002466513 bam 3.0 GB
EGAF00002466514 bam 5.5 GB
EGAF00002466515 bam 4.5 GB
EGAF00002466516 bam 2.9 GB
EGAF00002466517 bam 2.1 GB
EGAF00002466518 bam 4.0 GB
EGAF00002466519 bam 2.1 GB
EGAF00002466520 bam 1.3 GB
EGAF00002466521 bam 3.4 GB
EGAF00002466522 bam 3.8 GB
EGAF00002466523 bam 3.0 GB
EGAF00002466524 bam 2.7 GB
EGAF00002466525 bam 1.6 GB
EGAF00002466526 bam 3.4 GB
EGAF00002466527 bam 3.5 GB
EGAF00002466528 bam 3.1 GB
EGAF00002466529 bam 4.6 GB
EGAF00002466530 bam 4.0 GB
EGAF00002466531 bam 5.0 GB
EGAF00002466532 bam 6.1 GB
EGAF00002466533 bam 3.4 GB
EGAF00002466534 bam 3.0 GB
EGAF00002466535 bam 3.0 GB
EGAF00002466536 bam 3.3 GB
EGAF00002466537 bam 3.4 GB
EGAF00002466538 bam 5.7 GB
EGAF00002466539 bam 5.9 GB
EGAF00002466540 bam 3.3 GB
EGAF00002466541 bam 4.8 GB
EGAF00002466542 bam 3.3 GB
EGAF00002466543 bam 3.7 GB
EGAF00002466544 bam 4.6 GB
EGAF00002466545 bam 2.9 GB
EGAF00002466546 bam 3.8 GB
EGAF00002466547 bam 4.3 GB
EGAF00002466548 bam 2.7 GB
EGAF00002466549 bam 4.4 GB
EGAF00002466550 bam 3.5 GB
EGAF00002466551 bam 5.0 GB
199 Files (1.8 TB)